[藏药余甘子果实化学成分的研究]
[Studies on chemical constituents in fruits of Tibetan medicine Phyllanthus emblica].
作者信息
Zhang Lan-zhen, Zhao Wen-hua, Guo Ya-jian, Tu Guang-zhong, Lin Shu, Xin Lin-guang
机构信息
School of Chinese Pharmacy, Beijing University of Traditional Chinese Medicine, Beijing 100102, China.
出版信息
Zhongguo Zhong Yao Za Zhi. 2003 Oct;28(10):940-3.
OBJECTIVE
To investigate the chemical constituents of Tibetan medicine Phyllanthus emblica.
METHOD
Various chromatographic techniques were employed for isolation and purification of the constituents, and the structures were elucidated by chemical and spectral analyses.
RESULT
11 compounds were isolated and identified as gallic acid (I), ellagic acid (II), 1-O-galloyl-beta-D-glucose (III), 3,6-di-O-galloyl-D-glucose (IV), chebulinic acid (V), quercetin (VI), chebulagic acid (VII), corilagin (VIII), 3-ethylgallic acid (3-ethoxy-4,5-dihydroxy-benzoic acid, IX), isostrictiniin (X), 1,6-di-O-galloyl-beta-D-glucose (XI).
CONCLUSION
3-Ethylgallic acid (3-ethoxy-4,5-dihydroxy-benzoic acid) is a novel compound, and isostrictiniin was found from P. emblica for the first time.
目的
研究藏药余甘子的化学成分。
方法
采用多种色谱技术对其成分进行分离纯化，并通过化学和光谱分析阐明其结构。
结果
分离鉴定出11种化合物，分别为没食子酸（I）、鞣花酸（II）、1-O-没食子酰基-β-D-葡萄糖（III）、3,6-二-O-没食子酰基-D-葡萄糖（IV）、诃子次酸（V）、槲皮素（VI）、诃子鞣酸（VII）、柯里拉京（VIII）、3-乙基没食子酸（3-乙氧基-4,5-二羟基苯甲酸，IX）、异诃子素（X）、1,6-二-O-没食子酰基-β-D-葡萄糖（XI）。
结论
3-乙基没食子酸（3-乙氧基-4,5-二羟基苯甲酸）为新化合物，异诃子素首次从余甘子中发现。
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