Tribouilloy C, Mirode A, Marek A, Rey J L, Avinée P, Lesbre J P
Service de cardiologie B, hôpital Sud, Amiens.
Arch Mal Coeur Vaiss. 1992 Feb;85(2):193-8.
The aim of this study was to assess the value and limitations of Doppler echocardiographic measurement of aortic flow in the quantification of aortic regurgitation. Sixty-one patients were examined by Doppler echocardiography within 48 hours of cardiac catheterisation. There were 9 Grade I, 18 Grade II, 18 Grade III and 16 Grade IV angiographic aortic regurgitations. The mean aortic blood flow in angiographic Grades I and II (p less than 0.01). A correlation was observed between Doppler aortic flow and the angiographic grade of regurgitation (r = 0.66, p less than 0.001) and between aortic flow and regurgitant fraction (r = 0.68, p less than 0.001). Aortic flow greater than 10 l/mn identified angiographic Grades III or IV regurgitation with a sensitivity and specificity of 73.5% and 92.5% respectively and a positive and negative predictive values of 92.5% and 73.5% respectively. Aortic regurgitation with a regurgitant fraction greater than 40% was identified by a pulsed Doppler aortic blood flow greater than 10 l/mn with a sensitivity and specificity of 70% and 93% respectively, and positive and negative predictive values of 95% and 61% respectively. The sensitivity of this criterion is relatively poor as some severe aortic regurgitations have aortic flows of less than 10 l/mn: these patients have low outputs because of left ventricular dysfunction which is apparent from measurement of left ventricular fractional shortening.
本研究的目的是评估多普勒超声心动图测量主动脉血流在定量主动脉瓣反流中的价值和局限性。61例患者在心脏导管插入术48小时内接受了多普勒超声心动图检查。血管造影显示有9例I级、18例II级、18例III级和16例IV级主动脉瓣反流。血管造影I级和II级的平均主动脉血流量(p小于0.01)。观察到多普勒主动脉血流与反流的血管造影分级之间存在相关性(r = 0.66,p小于0.001),以及主动脉血流与反流分数之间存在相关性(r = 0.68,p小于0.001)。主动脉血流大于10 l/分钟可识别血管造影III级或IV级反流,敏感性和特异性分别为73.5%和92.5%,阳性和阴性预测值分别为92.5%和73.5%。反流分数大于40%的主动脉瓣反流可通过脉冲多普勒主动脉血流大于10 l/分钟识别,敏感性和特异性分别为70%和93%,阳性和阴性预测值分别为95%和61%。该标准的敏感性相对较差,因为一些严重的主动脉瓣反流患者的主动脉血流小于10 l/分钟:这些患者由于左心室功能障碍导致心输出量低,这从左心室缩短分数的测量中可以明显看出。