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[主动脉瓣关闭不全的定量分析。多普勒超声心动图与定性血管造影方法的比较:关于连续60例患者的系列研究]

[Quantification of aortic insufficiencies. Comparison between Doppler echocardiography and qualitative angiographic methods: apropos of a series of 60 consecutive patients].

作者信息

Halary J J, Vanzetto G, Mann H, Hadjian O, Defaye P, Mansour P, Petit L, Bertrand B, Contard M, Machecourt J

机构信息

Clinique cardiologique et urgences cardiologiques, CHU de Grenoble.

出版信息

Arch Mal Coeur Vaiss. 1995 Apr;88(4):471-8.

PMID:7646265
Abstract

Many doppler echocardiographic indices have been described for quantifying aortic regurgitation, posing the problem of the relative value of each. Therefore, the authors assessed the severity of aortic regurgitation in 60 consecutive patients (16 women and 44 men, mean age 56.7 years, range 7 to 84 years) by the four grades of Seller's classification with selective aortography. These results were compared with Doppler echocardiographic measurement of anterograde cardiac output (Qao), the pressure half time (PHT), diameter of the jet at its origin in M mode colour Doppler (DTM) and calculation of the regurgitant fraction (RF) by comparison of flow at the different cardiac orifices by a method previously described and validated in the author's laboratory with an interorifice correlation of 0.91 to 0.96 and confidence intervals at 95% of the order of 12%. The feasibility of doppler echocardiographic methods was good: 87.8% for PHT (58/66 patients), 90% for DTM (36/40 patients), 90.9% for Qao and RF (60/66 patients). The correlation with aortography was -0.65 (p < 0.01) for PHT; 0.91 (p < 0.01) for DTM, 0.80 (p < 0.01) for Qao and 0.92 (p < 0.005) for RF. However, there was a number of overlaps between Grades I and II and Grades III and IV.(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

已有许多多普勒超声心动图指标用于量化主动脉瓣反流,这就产生了各指标相对价值的问题。因此,作者通过Seller分级的四个等级并结合选择性主动脉造影,对60例连续患者(16例女性和44例男性,平均年龄56.7岁,年龄范围7至84岁)的主动脉瓣反流严重程度进行了评估。将这些结果与多普勒超声心动图测量的正向心输出量(Qao)、压力半衰期(PHT)、M型彩色多普勒中射流起始处的直径(DTM)以及通过先前在作者实验室中描述并验证的方法,通过比较不同心脏口的血流来计算反流分数(RF)进行比较,口间相关性为0.91至0.96,95%置信区间约为12%。多普勒超声心动图方法的可行性良好:PHT为87.8%(58/66例患者),DTM为90%(36/40例患者),Qao和RF为90.9%(60/66例患者)。PHT与主动脉造影的相关性为-0.65(p<0.01);DTM为0.91(p<0.01),Qao为0.80(p<0.01),RF为0.92(p<0.005)。然而,I级和II级以及III级和IV级之间存在一些重叠。(摘要截短于250字)

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