Apea-Kubi Kwasi Akyem, Yamaguchi Shinya, Sakyi Bright, Kishimoto Toshio, Ofori-Adjei David, Hagiwara Toshikatsu
Department of Obstetrics and Gynaecology, University of Ghana Medical School, Korle-Bu Teaching Hospital, Accra, Ghana.
Jpn J Infect Dis. 2004 Dec;57(6):253-6.
Five hundred and seventeen women attending the gynecology and obstetrics clinics of the Korle-Bu Teaching Hospital were examined for sexually transmitted infections (STIs). Vaginal swabs were examined for Trichomonas vaginalis, Candida albicans, and Gardnerella vaginalis infection. Endocervical swabs were examined for Neisseria gonorrhoea and Chlamydia trachomatis using a recently developed RNA detection kit. Strain typing was performed to identify serovars of C. trachomatis. Sera were analyzed for Treponema pallidum with a passive-particle agglutination assay kit. The prevalence of infection with N. gonorrhoea was 0.6%, C. trachomatis 3.0%, and T. pallidum 5.6%. Eight samples were PCR-positive for C. trachomatis. Five of these were serovar G, and the rest were serovar E. All cases of mixed infections occurred in pregnant women. In conclusion, a high transmissible risk of T. pallidum infection was observed among our study population and in particular among our pregnant women. The absence of association between the presenting symptoms, clinical findings, and specific pathogens has implications for the syndromic approach to STI case management. The low prevalence of C. trachomatis and N. gonorrhoea may be due to self medication and requires further research in primary health institutions in rural areas to compare rates.
对517名前往科勒-布教学医院妇产科门诊的女性进行了性传播感染（STIs）检查。对阴道拭子进行了阴道毛滴虫、白色念珠菌和阴道加德纳菌感染检测。使用最近开发的RNA检测试剂盒对宫颈拭子进行淋病奈瑟菌和沙眼衣原体检测。进行菌株分型以鉴定沙眼衣原体的血清型。使用被动颗粒凝集试验试剂盒分析血清中的梅毒螺旋体。淋病奈瑟菌感染率为0.6%，沙眼衣原体为3.0%，梅毒螺旋体为5.6%。8份样本沙眼衣原体PCR检测呈阳性。其中5份为血清型G，其余为血清型E。所有混合感染病例均发生在孕妇中。总之，在我们的研究人群中，尤其是孕妇中，观察到梅毒螺旋体感染的高传播风险。症状、临床发现与特定病原体之间缺乏关联，这对性传播感染病例管理的综合征方法有影响。沙眼衣原体和淋病奈瑟菌的低感染率可能是由于自我用药，需要在农村地区的初级卫生机构进行进一步研究以比较发病率。
