Kosmahl M, Pauser U, Anlauf M, Sipos B, Peters K, Lüttges J, Klöppel G
Institut für Allgemeine Pathologie, Universitätsklinikum Schleswig-Holstein--Campus Kiel, Michaelisstrasse 11, 24105 Kiel, Germany.
Pathologe. 2005 Feb;26(1):22-30. doi: 10.1007/s00292-004-0734-1.
Cystic tumors and tumor-like lesions of the pancreas are rare, but have attracted a great deal of attention because they are easily recognized with new imaging methods and, in contrast to ductal adenocarcinoma, they can usually be cured surgically. The increasing resection rate in recent years has also increased our knowledge of cystic pancreatic tumors by conspicuously enlarging their morphological spectrum. Known entities have been better characterized (i.e. solid pseudopapillary neoplasm, intraductal papillary mucinous neoplasm) and new ones described (serous oligocystic adenoma, mucinous non-neoplastic cyst, acinar cell cystadenoma and cystic hamartoma). This review discusses the most important cystic tumors and tumor-like lesions, presents a new classification, and summarizes the immunohistochemical differential diagnosis.
胰腺囊性肿瘤及肿瘤样病变较为罕见，但由于借助新的成像方法易于识别，且与导管腺癌不同，通常可通过手术治愈，因此备受关注。近年来切除率的提高显著拓宽了胰腺囊性肿瘤的形态学谱，也增加了我们对其的认识。已知的实体病变得到了更好的特征描述（如实性假乳头状瘤、导管内乳头状黏液性肿瘤），并发现了新的病变（浆液性寡囊性腺瘤、黏液性非肿瘤性囊肿、腺泡细胞囊腺瘤和囊性错构瘤）。本文综述了最重要的囊性肿瘤及肿瘤样病变，提出了一种新的分类方法，并总结了免疫组化鉴别诊断。
