Heitz James W, Viscusi Eugene R
Department of Anesthesiology, Thomas Jefferson University, 111 South 11th Street, Suite G8490, Philadelphia, PA 19107-5092, USA. james.heitz @jefferson.edu
Curr Pain Headache Rep. 2005 Feb;9(1):17-23. doi: 10.1007/s11916-005-0070-z.
Local anesthetics and opioids were among the earliest pharmacologic agents used for intrathecal injection. Side-effect profiles have limited the use of additional agents and, after a century of clinical use, local anesthetics and opioids remain the most widely used intrathecal or epidural medications.
局部麻醉药和阿片类药物是最早用于鞘内注射的药物之一。副作用限制了其他药物的使用,经过一个世纪的临床应用,局部麻醉药和阿片类药物仍然是最广泛使用的鞘内或硬膜外用药。