Nostrant Timothy T
University of Michigan Health Center, 3912 Taubman Center, 1500 E. Medical Center Drive, Ann Arbor, MI 48109-0362, USA.
Curr Treat Options Gastroenterol. 2005 Feb;8(1):85-95. doi: 10.1007/s11938-005-0054-4.
Esophageal dilation is the treatment of choice for most patients with esophageal dysphagia (functional and mechanical). Multiple forms of esophageal dilators are available. Mechanical dilators (guidewire/nonguidewire assisted) are the major forms of dilators used. Balloon dilator use has increased but they offer only a marginal advantage over traditional mechanical dilators at a greatly increased cost (2 degrees to single use). Comparative trials are biased in favor of balloon dilators, but balloon dilators are not indicated for empiric dilation for dysphagia. Empiric dilation for solid food dysphagia is still controversial. Dilation is rarely associated with complications and is rarely contraindicated unless previous dilation attempts have been unsuccessful. Special circumstances such as caustic strictures, radiation stricture, and dysphagia associated with eosinophilic esophagitis should engender cautious dilation. Attention to detail about placement of guidewires and stricture type are still critical for safety. Predilation barium studies are not needed in all patients but should be employed if the endoscope is not able to pass the stricture and stricture length and angulation are unknown. Intralesional steroids and proton pump inhibitor therapy are important adjuvant treatments for resistant strictures and reflux associated strictures. Balloon dilation for achalasia is still a viable alternative, but it is likely to decrease in usage with the advent of more widespread laparoscopic myotomy.
食管扩张术是大多数食管吞咽困难(功能性和机械性)患者的首选治疗方法。有多种形式的食管扩张器可供使用。机械扩张器(导丝辅助/非导丝辅助)是主要使用的扩张器形式。球囊扩张器的使用有所增加,但与传统机械扩张器相比,其优势甚微,且成本大幅增加(因一次性使用)。比较试验偏向于球囊扩张器,但球囊扩张器并不适用于吞咽困难的经验性扩张。固体食物吞咽困难的经验性扩张仍存在争议。扩张很少与并发症相关,除非先前的扩张尝试失败,否则很少有禁忌证。诸如腐蚀性狭窄、放射性狭窄以及与嗜酸性食管炎相关的吞咽困难等特殊情况应谨慎进行扩张。对于安全性而言,关注导丝放置细节和狭窄类型仍然至关重要。并非所有患者都需要进行扩张前钡剂检查,但如果内镜无法通过狭窄且狭窄长度和角度未知,则应采用此项检查。病灶内注射类固醇和质子泵抑制剂治疗是难治性狭窄和反流相关狭窄的重要辅助治疗方法。球囊扩张术治疗贲门失弛缓症仍是一种可行的替代方法,但随着腹腔镜下肌切开术的更广泛应用,其使用可能会减少。