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新德里8年经验:79例成人酸碱所致食管狭窄的内镜扩张治疗

Management of acid- and alkali-induced esophageal strictures in 79 adults by endoscopic dilation: 8-years' experience in New Delhi.

作者信息

Singhal Shashideep, Kar Premashis

机构信息

Gastroenterology Division, Department of Medicine, Maulana Azad Medical College and Lok Nayak Hospital, New Delhi, India.

出版信息

Dysphagia. 2007 Apr;22(2):130-4. doi: 10.1007/s00455-006-9064-1. Epub 2007 Feb 14.

Abstract

Experience with endoscopic dilation of acid- and alkali-induced strictures of the esophagus using Savary-Gilliard (SG) and balloon dilators is limited, especially in adults. The aim of this study was to determine the safety and efficacy of endoscopic dilation in the management of corrosive esophageal strictures and to compare results with regard to acid- vs. alkali-induced strictures. The records of 230 patients who were treated by endoscopic dilation between 1997 and 2005 at our center were reviewed. This study included all the patients who had corrosive-induced esophageal strictures. SG dilators were used in most of our patients [67/79 (85%)], while only a few patients [12/79 (15%)] were treated with balloon dilators. Dilation was found to be successful after an initial course of dilation (not requiring further dilations) in 28/37 (75.67%) cases in the SG dilator group and in 9/12 (75%) in the balloon group. Strictures caused by acids required a greater mean number of dilations for initial relief of dysphagia compared with that for alkalis. Some of these patients responded to a second course of dilation, leading to final combined SG dilator and balloon dilator success rates of 24/28 (86%) in the acid group and 17/21 (81%) in the alkali group. A total of 359 sessions of dilations were performed with a complication rate of 2/359 (0.56%). Endoscopic dilation using Savary-Gilliard and balloon dilators is safe and effective in managing corrosive esophageal strictures, but it is operator-dependent and the final outcome depends largely on the technical expertise and appropriate selection of patients.

摘要

使用Savary-Gilliard(SG)扩张器和球囊扩张器对酸碱所致食管狭窄进行内镜扩张的经验有限,尤其是在成人患者中。本研究的目的是确定内镜扩张治疗腐蚀性食管狭窄的安全性和有效性,并比较酸碱所致狭窄的治疗结果。回顾了1997年至2005年在我们中心接受内镜扩张治疗的230例患者的记录。本研究纳入了所有患有腐蚀性食管狭窄的患者。我们的大多数患者[67/79(85%)]使用SG扩张器,而只有少数患者[12/79(15%)]接受球囊扩张器治疗。在SG扩张器组中,28/37(75.67%)的病例在初始扩张疗程后(无需进一步扩张)扩张成功,球囊组为9/12(75%)。与碱所致狭窄相比,酸所致狭窄在初始缓解吞咽困难时平均需要更多次数的扩张。其中一些患者对第二疗程的扩张有反应,最终酸组SG扩张器和球囊扩张器联合成功率为24/28(86%),碱组为17/2

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