Hwang In Taek, Kim Hyoung Rae, Jeon Dong Ju, Hong Kyung Sik, Song Jong Hwan, Chung Chang Kook, Cho Kwang Yun
Korea Research Institute of Chemical Technology, Bioorganic Science Division, Yusung, Taejon 305-606, Korea.
Pest Manag Sci. 2005 May;61(5):483-90. doi: 10.1002/ps.992.
A series of 3-chloro-2-(4-chloro-2-fluorophenyl)-4,5,6,7-tetrahydro-2H-indazole derivatives containing various substituted isoxazolinylmethoxy groups at the 5-position of the benzene ring were synthesized and their herbicidal activities assessed under greenhouse and flooded paddy conditions. Among them, compounds having a phenyl or cyano substituent at the 3-position of the 5-methyl-isoxazolin-5-yl structure demonstrated good rice selectivity and potent herbicidal activity against annual weeds at 16-63 g AI ha(-1) under greenhouse conditions. Field trials indicated that these two compounds controlled a wide range of annual weeds rapidly with a good tolerance on transplanted rice seedlings by pre-emergence application. They showed a low mammalian and environmental toxicity in various toxicological tests.
