Hwang In Taek, Kim Hyoung Rae, Jeon Dong Ju, Hong Kyung Sik, Song Jong Hwan, Cho Kwang Yun
Korea Research Institute of Chemical Technology, Yuseong, Taejon 305-606, Korea.
J Agric Food Chem. 2005 Nov 2;53(22):8639-43. doi: 10.1021/jf051284f.
5-(2,6-difluorobenzyl)oxymethyl-5-methyl-3-(3-methylthiophen-2-yl)-1,2-isoxazoline derivative was synthesized, and its herbicidal activity was assessed under glasshouse and flooded paddy conditions. 5-(2,6-Difluorobenzyl)oxymethyl-5-methyl-3-(3-methylthiophen-2-yl)-1,2-isoxazoline demonstrated good rice selectivity and potent herbicidal activity against annual weeds at 125 g of a.i. ha(-1) under greenhouse conditions. Soil application of this compound showed complete control of barnyard-grass to the fourth leaf stage at 250 g of a.i. ha(-1). Field trials indicated that this compound controlled annual weeds rapidly with a good tolerance on transplanted rice seedlings by post-emergence and soil application. This compound showed a low mammalian and environmental toxicity in various toxicological tests.
合成了5-(2,6-二氟苄基)氧甲基-5-甲基-3-(3-甲基噻吩-2-基)-1,2-异恶唑啉衍生物，并在温室和淹水水稻条件下评估了其除草活性。5-(2,6-二氟苄基)氧甲基-5-甲基-3-(3-甲基噻吩-2-基)-1,2-异恶唑啉在温室条件下，以125 g a.i. ha(-1)的剂量对一年生杂草表现出良好的水稻选择性和强效除草活性。该化合物土壤施用时，在250 g a.i. ha(-1)剂量下对稗草的防除效果可达第四叶期。田间试验表明，该化合物通过苗后和土壤施用对一年生杂草的防除迅速，对移栽水稻幼苗具有良好的耐受性。该化合物在各种毒理学试验中显示出低哺乳动物毒性和环境毒性。
