Fahey J L, Schooley R
Center for Interdisciplinary Research and Disease, UCLA School of Medicine 90024-1747.
Clin Exp Immunol. 1992 Apr;88(1):1-5. doi: 10.1111/j.1365-2249.1992.tb03029.x.
As our understanding of HIV disease pathogenesis progresses, approaches to immune-based therapy are evolving. Initial therapies aiming to alter immune function in patients with HIV infection have had mixed results. Clinical benefit in the trials so far has not been dramatic, although the studies are still at an early stage, and the correct protocols for the various agents or combinations of agents have yet to be established. As might be expected, where apparent benefit has occurred, it has been more obvious in those patients whose immune system was still intact.
随着我们对HIV疾病发病机制的理解不断深入，基于免疫的治疗方法也在不断发展。最初旨在改变HIV感染患者免疫功能的治疗方法效果不一。尽管这些研究仍处于早期阶段，各种药物或药物组合的正确方案尚未确立，但迄今为止试验中的临床益处并不显著。不出所料，在出现明显益处的地方，在免疫系统仍完好无损的患者中更为明显。
