多聚物溶液相反应：在光延反应中的应用。

Multipolymer solution-phase reactions: application to the Mitsunobu reaction.

作者信息

Harned Andrew M, He Helen Song, Toy Patrick H, Flynn Daniel L, Hanson Paul R

机构信息

Department of Chemistry, University of Kansas, 1251 Wescoe Hall Drive, Lawrence, Kansas 66045, USA.

出版信息

J Am Chem Soc. 2005 Jan 12;127(1):52-3. doi: 10.1021/ja045188r.

DOI:10.1021/ja045188r

PMID:15631444

Abstract

The realization of the first polymer-on-polymer Mitsunobu reaction, in which a polymeric phosphine is used simultaneously with a polymeric azodicarboxylate, is reported. This strategy employs the use of soluble oligomers generated from ring-opening methathesis polymerization. 31P NMR analysis revealed that the two polymers were interacting to generate the Mitsunobu products. Application to several substrates, as well as comparison experiments with other polymeric reagents, is described.

摘要

报道了首例聚合物-聚合物之间的光延反应，该反应中同时使用了聚合物膦和聚合物偶氮二甲酸酯。此策略采用了由开环易位聚合生成的可溶性低聚物。31P核磁共振分析表明，这两种聚合物相互作用生成了光延反应产物。文中描述了该反应在几种底物上的应用以及与其他聚合物试剂的对比实验。