放疗后复发性喉癌的手术治疗：行部分喉切除术还是全喉切除术以获得更好的生活质量？

Surgery for recurrent laryngeal carcinoma after radiotherapy: partial laryngectomy or total laryngectomy for a better quality of life?

作者信息

Sewnaik Aniel, van den Brink Jaap L, Wieringa Marjan H, Meeuwis Cees A, Kerrebijn Jeroen D F

机构信息

Department of Otolaryngology-Head and Neck Surgery, Erasmus Medical Center Rotterdam, The Netherlands.

出版信息

Otolaryngol Head Neck Surg. 2005 Jan;132(1):95-8. doi: 10.1016/j.otohns.2004.09.011.

DOI:10.1016/j.otohns.2004.09.011

PMID:15632916

Abstract

OBJECTIVE

To investigate the quality of life after partial laryngectomy versus total laryngectomy for recurrent laryngeal carcinomas after radiotherapy.

STUDY DESIGN AND SETTING

A retrospective study performed at least one year after treatment. This study was performed in a university hospital.

RESULTS

Twenty-three patients (N = 12 partial laryngectomy, N = 11 total laryngectomy) with recurrent laryngeal cancer after radiotherapy were included in the study. Three different questionnaires, 1) EORTC Quality of Life Questionnaire (QLQ)-C30 Dutch version 3.0, 2) EORTC-H & N 35, and 3) the Voice Handicap Index, were sent to all patients. The only major difference in quality of life of patients after partial laryngectomy versus total laryngectomy was found to be smell and taste related. No other differences were found.

CONCLUSION

We did not find much difference in quality of life after treatment with a partial laryngectomy or a total laryngectomy in patients with recurrent laryngeal cancer after radiotherapy.

摘要

目的

探讨放疗后复发性喉癌患者行部分喉切除术与全喉切除术的生活质量。

研究设计与地点

一项在治疗后至少一年进行的回顾性研究。本研究在一家大学医院开展。

结果

本研究纳入了23例放疗后复发性喉癌患者（12例行部分喉切除术，11例行全喉切除术）。向所有患者发放了三种不同的问卷：1）欧洲癌症研究与治疗组织生活质量问卷（QLQ）-C30荷兰语版3.0；2）欧洲癌症研究与治疗组织头颈部问卷（EORTC-H&N）35；3）嗓音障碍指数。结果发现，部分喉切除术患者与全喉切除术患者生活质量的唯一主要差异与嗅觉和味觉有关。未发现其他差异。