Van Wyk F C, Vaz F, Harries M, Weighill J
Department of ENT Surgery, Royal Sussex County Hospital, Brighton, UK.
J Laryngol Otol. 2008 Sep;122(9):967-71. doi: 10.1017/S0022215107000357. Epub 2007 Oct 1.
Several studies have implied that patients' quality of life stabilises six months after undergoing total laryngectomy. However, these studies may well have overlooked persistent short term variations in patients' quality of life. The aim of this study was to assess the impact of seasonal change (i.e. summer vs winter) on the quality of life of patients following total laryngectomy.
A prospective, cross-sectional study of recurrence-free laryngectomy patients was performed, using the European Organization for Research and Treatment of Cancer (version three) QLQ-C30 questionnaires (EORTC QLQ-C30), during January 2004 (i.e. winter), August 2004 (summer) and January 2005 (winter).
Thirty-six patients were entered into the study. The response rate was 70.3 per cent. Patient's time elapsed since surgery varied from six months to 12 years. In all questionnaire domains, responses seemed remarkably consistent over time.
No statistically significant differences were found between summer and winter scores in all the domains analysed by the EORTC QLQ-C30.
多项研究表明,全喉切除术后患者的生活质量在六个月后趋于稳定。然而,这些研究很可能忽略了患者生活质量持续存在的短期变化。本研究的目的是评估季节变化(即夏季与冬季)对全喉切除术后患者生活质量的影响。
对无复发的喉切除患者进行了一项前瞻性横断面研究,在2004年1月(冬季)、2004年8月(夏季)和2005年1月(冬季)使用欧洲癌症研究与治疗组织(第三版)QLQ-C30问卷(EORTC QLQ-C30)。
36名患者进入研究。应答率为70.3%。患者术后时间从六个月到十二年不等。在所有问卷领域,随着时间的推移,回答似乎非常一致。
在EORTC QLQ-C30分析的所有领域中,夏季和冬季得分之间未发现统计学上的显著差异。