Al-Brahim Nabeel, Alowami Salem, Davis Ian, Daya Dean
Department of Pathology, McMaster University, Henderson General Hospital, Hamilton, Ontario, Canada.
Can J Urol. 2004 Dec;11(6):2463-6.
An 83- year-old male presented with intermittent hematuria and obstructive symptoms. A CT scan of the abdomen and pelvis showed diffuse thickening of the urinary bladder and a large 10 cm liver mass. Histopathological examination of bladder biopsy demonstrated two distinct lesions. The surface showed non-invasive urothelial carcinoma and the submucosa demonstrated metastatic hepatocellular carcinoma showing bile pigment and expressed Hep Par 1 and CD10. To the best of our knowledge, this is the first case report of synchronous transitional cell carcinoma and metastatic hepatocellular carcinoma of the urinary bladder.
一名83岁男性出现间歇性血尿和梗阻症状。腹部和盆腔CT扫描显示膀胱弥漫性增厚以及肝脏有一个10厘米的大肿块。膀胱活检的组织病理学检查显示有两个不同的病变。表面显示为非浸润性尿路上皮癌，黏膜下层显示为转移性肝细胞癌，有胆汁色素，表达Hep Par 1和CD10。据我们所知，这是膀胱同时发生移行细胞癌和转移性肝细胞癌的首例病例报告。
