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两例暴发性脑膜炎球菌性紫癜:“少即是多”的治疗方法

Two cases of meningococcal purpura fulminans: the 'less is more' approach.

作者信息

Ahmad Zeeshan, Jordan Robert, Das-Gupta Rana, Srivastava Shekhar

机构信息

Department of Plastic and Reconstructive Surgery, University Hospitals of Coventry and Warwickshire, Coventry, Warwickshire, UK.

出版信息

Int Wound J. 2014 Dec;11(6):636-40. doi: 10.1111/iwj.12020. Epub 2013 Jan 17.

Abstract

This study presents a case series of patients with meningococcal purpura fulminans who were treated at a tertiary referral centre within a few days of each other. Presenting with signs and symptoms of florid meningococcal sepsis, they were managed initially by physicians and intensivists, whereas the development of large purpuric areas and tissue necrosis was managed expectantly by plastic surgeons. When the patients were deemed to have recovered clinically and the necrosis delineated, surgical management was implemented with subsequent involvement of various rehabilitation services. This article highlights the cases of two patients, and their clinical presentation, management and rehabilitation together with a current literature review on this area.

摘要

本研究报告了一系列暴发性脑膜炎球菌紫癜患者的病例,这些患者在几天内相继在一家三级转诊中心接受治疗。他们表现出明显的脑膜炎球菌败血症的体征和症状,最初由内科医生和重症监护医生进行治疗,而大面积紫癜区域和组织坏死的情况则由整形外科医生进行观察处理。当患者被认为临床康复且坏死情况明确后,实施了手术治疗,随后还涉及了各种康复服务。本文重点介绍了两名患者的病例,包括他们的临床表现、治疗和康复情况,并对该领域的当前文献进行了综述。

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本文引用的文献

3
Prospects for vaccine prevention of meningococcal infection.脑膜炎球菌感染疫苗预防的前景。
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