Béhin Anthony, Delattre Jean-Yves
Fédération de Neurologie Mazarin, Groupe Hospitalier Pitié-Salpêtrière, 47-83 Boulevard de l'Hôpital, 75651 Paris Cedex 13, France.
Semin Neurol. 2004 Dec;24(4):405-17. doi: 10.1055/s-2004-861535.
Various nervous system complications can result from radiation therapy. Usually classified according to the timing of onset after irradiation, these complications can be debilitating and even life-threatening. A better knowledge of the risk factors has allowed the definition of "safe" procedures that have reduced the incidence of severe sequelae. This review addresses the main clinical, radiological, biological, and therapeutic issues pertaining to the side effects of radiation therapy on the brain and spinal cord, including radiation-induced vascular and endocrine complications.
放射治疗可导致多种神经系统并发症。这些并发症通常根据放疗后发病时间进行分类，可能使人虚弱，甚至危及生命。对风险因素的更深入了解使得能够定义“安全”程序，从而降低了严重后遗症的发生率。本综述探讨了与放疗对脑和脊髓的副作用相关的主要临床、放射学、生物学和治疗问题，包括放射性血管和内分泌并发症。
