Rattigan Stephen, Wheatley Catherine, Richards Stephen M, Barrett Eugene J, Clark Michael G
Department of Biochemistry, Medical School, University of Tasmania, Private Bag 58, Hobart, Tasmania, 7001, Australia.
Exerc Sport Sci Rev. 2005 Jan;33(1):43-8.
Blood flow to contracting muscles is increased rapidly and is redistributed within the muscle. Recent research has highlighted that insulin causes similar changes, but these are absent in insulin resistance, resulting in impaired insulin-mediated muscle glucose uptake. Understanding the mechanisms and interactions between contraction- and insulin-mediated alterations in blood flow within muscle may reveal new approaches to overcome insulin resistance.
流向收缩肌肉的血流量迅速增加，并在肌肉内重新分布。最近的研究强调，胰岛素会引起类似的变化，但在胰岛素抵抗中这些变化不存在，导致胰岛素介导的肌肉葡萄糖摄取受损。了解肌肉内收缩和胰岛素介导的血流改变之间的机制和相互作用，可能会揭示克服胰岛素抵抗的新方法。
