Whitfield Keith E, McClearn Gerald
Department of Biobehavioral Health, Pennsylvania State University, University Park, PA 16802, USA.
Am Psychol. 2005 Jan;60(1):104-14. doi: 10.1037/0003-066X.60.1.104.
Understanding the origins of racial health disparities is currently a central focus of health-oriented funding agencies and the health policy community. In particular, the role of genetics in the origin of racial health disparities is receiving growing attention and has been susceptible to considerable misinterpretation. In this article, the authors provide a basic discussion about the concept of genes and race, an introduction to quantitative genetics, and some examples of quantitative genetic analyses of health conditions in an underserved population. The intent is to outline the conceptual limitations of exclusivist views of either environmental or genetic determination and to emphasize the coaction and interaction of genes and environments in health.
了解种族健康差异的根源是目前以健康为导向的资助机构和卫生政策界的核心关注点。特别是，遗传学在种族健康差异起源中的作用受到越来越多的关注，并且容易产生相当多的误解。在本文中，作者提供了关于基因和种族概念的基本讨论、数量遗传学的介绍，以及对一个服务不足人群健康状况进行数量遗传分析的一些例子。目的是概述环境或基因决定论排他性观点的概念局限性，并强调基因与环境在健康方面的共同作用和相互作用。
