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Vasodilator constituents from the roots of Lysidice rhodostega.

作者信息

Gao Song, Feng Nan, Yu Shishan, Yu Dequan, Wang Xiaoliang

机构信息

Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, People's Republic of China.

出版信息

Planta Med. 2004 Dec;70(12):1128-34. doi: 10.1055/s-2004-835839.

Abstract

Two new phloroglucinol glycosides, lysidisides A and B, and two new flavanol ramifycations, lysidicichin and mopanolside, together with (+)-mopanol, polydatin and E-resveratrol 3-O-beta-D-xylopyranoside were isolated from the EtOAc extract of the roots of Lysidice rhodostega. The structures of the new compounds were elucidated on the basis of chemical and spectral evidence. Lysidisides A and B, (+)-mopanol and polydatin inhibited phenylepherine (Phe)-induced vasoconstriction in the rat aortic rings in the presences of indomethacin (Indo) and Nomega-L-nitroarginine (L-NA).

摘要

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