Miles K A
Division of Clinical and Laboratory Investigation, Brighton & Sussex Medical School, University of Sussex, Falmer, Brighton, UK.
Neuroradiology. 2004 Dec;46 Suppl 2:s194-200. doi: 10.1007/s00234-004-1333-9.
Within recent years, the broad introduction of fast multi-detector computed tomography (CT) systems and the availability of commercial software for perfusion analysis have made cerebral perfusion imaging with CT a practical technique for the clinical environment. The technique is widely available at low cost, accurate and easy to perform. Perfusion CT is particularly applicable to those clinical circumstances where patients already undergo CT for other reasons, including stroke, head injury, subarachnoid haemorrhage and radiotherapy planning. Future technical developments in multi-slice CT systems may diminish the current limitations of limited spatial coverage and radiation burden. CT perfusion imaging on combined PET-CT systems offers new opportunities to improve the evaluation of patients with cerebral ischaemia or tumours by demonstrating the relationship between cerebral blood flow and metabolism. Yet CT is often not perceived as a technique for imaging cerebral perfusion. This article reviews the use of CT for imaging cerebral perfusion, highlighting its advantages and disadvantages and draws comparisons between perfusion CT and magnetic resonance imaging.
近年来，快速多探测器计算机断层扫描（CT）系统的广泛应用以及用于灌注分析的商业软件的出现，使得CT脑灌注成像成为临床环境中一种实用的技术。该技术成本低廉、广泛可用、准确且易于操作。灌注CT特别适用于那些患者因其他原因已经接受CT检查的临床情况，包括中风、头部损伤、蛛网膜下腔出血和放射治疗计划。多层CT系统未来的技术发展可能会减少当前空间覆盖有限和辐射负担方面的限制。在PET-CT联合系统上进行CT灌注成像，通过展示脑血流与代谢之间的关系，为改善脑缺血或肿瘤患者的评估提供了新的机会。然而，CT通常不被视为一种脑灌注成像技术。本文回顾了CT在脑灌注成像中的应用，突出其优缺点，并对灌注CT和磁共振成像进行了比较。
