Mnyusiwalla Anisa, Aviv Richard I, Symons Sean P
Department of Medical Imaging, Division of Neuroradiology, Sunnybrook Health Sciences Center, University of Toronto, Toronto, ON, Canada.
Neuroradiology. 2009 Oct;51(10):635-40. doi: 10.1007/s00234-009-0543-6. Epub 2009 Jun 9.
The objective of this study was to determine the radiation dose delivered during comprehensive computed tomography (CT) imaging for acute stroke.
All CT examinations performed over 18 months using our acute stroke protocol were included. Protocol includes an unenhanced CT head, CT angiography from the arch to vertex, CT perfusion/permeability, and an enhanced CT head. All imaging was acquired with a 64-MDCT. Examinations where any element of the protocol was repeated or omitted due to mistimed injection or patient motion were excluded. Dose-length products (DLP) for all components of each examination were obtained from dose reports generated at the time of acquisition, separating neck, and head calculations. Effective doses for each examination were calculated using the DLP and normalized values of effective dose per DLP appropriate for the body regions imaged.
Ninety-five examinations were included. Mean DLP was 6,790.0 mGy x cm. Effective doses ranged from 11.8 to 27.3 mSv, mean effective dose of 16.4 mSv. Mean effective dose for acquisition of the unenhanced head was 2.7 mSv. Largest contribution to effective dose was the CTA with a mean effective dose of 5.4 mSv. Mean effective dose for the CT perfusion was 4.9 mSv.
A comprehensive CT acute stroke protocol delivered a mean effective dose of 16.4 mSv, which is approximately six times the dose of an unenhanced CT head. These high-dose results must be balanced with the benefits of the detailed anatomic and physiologic data obtained. Centers should implement aggressive dose reduction strategies and freely use MR as a substitute.
本研究的目的是确定急性卒中综合计算机断层扫描(CT)成像期间的辐射剂量。
纳入了使用我们的急性卒中方案在18个月内进行的所有CT检查。方案包括头部平扫CT、从主动脉弓到颅顶的CT血管造影、CT灌注/通透性检查以及头部增强CT。所有成像均使用64层MDCT获取。因注射时间不当或患者移动导致方案中的任何部分被重复或遗漏的检查被排除。每次检查各部分的剂量长度乘积(DLP)从采集时生成的剂量报告中获取,分别计算颈部和头部的剂量。使用DLP和适用于成像身体区域的每DLP有效剂量归一化值计算每次检查的有效剂量。
纳入了95次检查。平均DLP为6790.0 mGy×cm。有效剂量范围为11.8至27.3 mSv,平均有效剂量为16.4 mSv。头部平扫的平均有效剂量为2.7 mSv。对有效剂量贡献最大的是CT血管造影,平均有效剂量为5.4 mSv。CT灌注的平均有效剂量为4.9 mSv。
急性卒中综合CT方案的平均有效剂量为16.4 mSv,约为头部平扫CT剂量的6倍。这些高剂量结果必须与所获得的详细解剖和生理数据的益处相权衡。各中心应实施积极的剂量降低策略,并自由使用磁共振成像(MR)作为替代。