• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

多排螺旋CT成像在急性脑卒中诊断中的辐射剂量

Radiation dose from multidetector row CT imaging for acute stroke.

作者信息

Mnyusiwalla Anisa, Aviv Richard I, Symons Sean P

机构信息

Department of Medical Imaging, Division of Neuroradiology, Sunnybrook Health Sciences Center, University of Toronto, Toronto, ON, Canada.

出版信息

Neuroradiology. 2009 Oct;51(10):635-40. doi: 10.1007/s00234-009-0543-6. Epub 2009 Jun 9.

DOI:10.1007/s00234-009-0543-6
PMID:19506845
Abstract

INTRODUCTION

The objective of this study was to determine the radiation dose delivered during comprehensive computed tomography (CT) imaging for acute stroke.

METHODS

All CT examinations performed over 18 months using our acute stroke protocol were included. Protocol includes an unenhanced CT head, CT angiography from the arch to vertex, CT perfusion/permeability, and an enhanced CT head. All imaging was acquired with a 64-MDCT. Examinations where any element of the protocol was repeated or omitted due to mistimed injection or patient motion were excluded. Dose-length products (DLP) for all components of each examination were obtained from dose reports generated at the time of acquisition, separating neck, and head calculations. Effective doses for each examination were calculated using the DLP and normalized values of effective dose per DLP appropriate for the body regions imaged.

RESULTS

Ninety-five examinations were included. Mean DLP was 6,790.0 mGy x cm. Effective doses ranged from 11.8 to 27.3 mSv, mean effective dose of 16.4 mSv. Mean effective dose for acquisition of the unenhanced head was 2.7 mSv. Largest contribution to effective dose was the CTA with a mean effective dose of 5.4 mSv. Mean effective dose for the CT perfusion was 4.9 mSv.

CONCLUSION

A comprehensive CT acute stroke protocol delivered a mean effective dose of 16.4 mSv, which is approximately six times the dose of an unenhanced CT head. These high-dose results must be balanced with the benefits of the detailed anatomic and physiologic data obtained. Centers should implement aggressive dose reduction strategies and freely use MR as a substitute.

摘要

引言

本研究的目的是确定急性卒中综合计算机断层扫描(CT)成像期间的辐射剂量。

方法

纳入了使用我们的急性卒中方案在18个月内进行的所有CT检查。方案包括头部平扫CT、从主动脉弓到颅顶的CT血管造影、CT灌注/通透性检查以及头部增强CT。所有成像均使用64层MDCT获取。因注射时间不当或患者移动导致方案中的任何部分被重复或遗漏的检查被排除。每次检查各部分的剂量长度乘积(DLP)从采集时生成的剂量报告中获取,分别计算颈部和头部的剂量。使用DLP和适用于成像身体区域的每DLP有效剂量归一化值计算每次检查的有效剂量。

结果

纳入了95次检查。平均DLP为6790.0 mGy×cm。有效剂量范围为11.8至27.3 mSv,平均有效剂量为16.4 mSv。头部平扫的平均有效剂量为2.7 mSv。对有效剂量贡献最大的是CT血管造影,平均有效剂量为5.4 mSv。CT灌注的平均有效剂量为4.9 mSv。

结论

急性卒中综合CT方案的平均有效剂量为16.4 mSv,约为头部平扫CT剂量的6倍。这些高剂量结果必须与所获得的详细解剖和生理数据的益处相权衡。各中心应实施积极的剂量降低策略,并自由使用磁共振成像(MR)作为替代。

相似文献

1
Radiation dose from multidetector row CT imaging for acute stroke.多排螺旋CT成像在急性脑卒中诊断中的辐射剂量
Neuroradiology. 2009 Oct;51(10):635-40. doi: 10.1007/s00234-009-0543-6. Epub 2009 Jun 9.
2
Effective dose to patient measurements for flat-detector computed tomography protocols in acute stroke care.用于急性脑卒中护理的平板探测器 CT 协议中患者测量的有效剂量。
Eur Radiol. 2020 Sep;30(9):5082-5088. doi: 10.1007/s00330-020-06891-w. Epub 2020 Apr 28.
3
Dose exposure of patients undergoing comprehensive stroke imaging by multidetector-row CT: comparison of 320-detector row and 64-detector row CT scanners.多排探测器 CT 对全面性脑卒中成像患者的剂量暴露:320 排与 64 排 CT 扫描仪的比较。
AJNR Am J Neuroradiol. 2010 Jun;31(6):1003-9. doi: 10.3174/ajnr.A1971. Epub 2010 Jan 28.
4
Radiation dose evaluation in multidetector-row CT imaging for acute stroke with an anthropomorphic phantom.多排螺旋 CT 成像评估急性脑卒中的辐射剂量:人体模型研究。
Br J Radiol. 2010 Dec;83(996):1029-41. doi: 10.1259/bjr/52267127.
5
Comparing Dose-Length Product-Based and Monte Carlo Simulation Organ-Based Calculations of Effective Dose in 16- and 64-MDCT Examinations Using Automatic Tube Current Modulation.比较基于剂量长度乘积和蒙特卡罗模拟器官计算的自动管电流调制在 16 层和 64 层 CT 检查中的有效剂量。
AJR Am J Roentgenol. 2018 Mar;210(3):583-592. doi: 10.2214/AJR.17.18294. Epub 2018 Jan 30.
6
Radiation Doses in Consecutive CT Examinations from Five University of California Medical Centers.来自加利福尼亚大学五所医学中心的连续CT检查中的辐射剂量。
Radiology. 2015 Oct;277(1):134-41. doi: 10.1148/radiol.2015142728. Epub 2015 May 19.
7
Enhancing acute stroke assessment: evaluating the clinical utility of the "Real" one-stop-shop scan protocol combining brain computed tomography perfusion and head-and-neck computed tomography angiography using a 512-slice detector computed tomography scanner.增强急性脑卒中评估:使用 512 层探测器 CT 扫描仪评估结合脑 CT 灌注和头颈部 CT 血管造影的“真正”一站式扫描方案的临床应用。
Clin Radiol. 2024 Nov;79(11):833-841. doi: 10.1016/j.crad.2024.07.023. Epub 2024 Aug 6.
8
Quantitative Dose Dependency Analysis of Whole-Brain CT Perfusion Imaging.全脑 CT 灌注成像的定量剂量依赖性分析。
Radiology. 2016 Jan;278(1):190-7. doi: 10.1148/radiol.2015142230. Epub 2015 Jun 25.
9
Radiation exposure to patients in a multicenter coronary angiography trial (CORE 64).多中心冠状动脉造影试验(CORE 64)中患者的辐射暴露。
AJR Am J Roentgenol. 2011 May;196(5):1126-32. doi: 10.2214/AJR.09.3983.
10
Radiation exposure of patients in comprehensive computed tomography of the head in acute stroke.急性卒中患者头部综合计算机断层扫描中的辐射暴露
AJNR Am J Neuroradiol. 2006 Sep;27(8):1741-5.

引用本文的文献

1
Radiomics machine learning based on asymmetrically prominent cortical and deep medullary veins combined with clinical features to predict prognosis in acute ischemic stroke: a retrospective study.基于不对称突出的皮质和深部髓质静脉的影像组学机器学习联合临床特征预测急性缺血性卒中的预后:一项回顾性研究
PeerJ. 2025 Jun 6;13:e19469. doi: 10.7717/peerj.19469. eCollection 2025.
2
Optimizing Radiation Dose and Image Quality in Stroke CT Protocols: Proposed Diagnostic Reference Levels for Multiphase CT Angiography and Perfusion Imaging.优化卒中CT方案中的辐射剂量与图像质量:多期CT血管造影和灌注成像的拟诊参考水平
Diagnostics (Basel). 2024 Dec 20;14(24):2866. doi: 10.3390/diagnostics14242866.
3

本文引用的文献

1
Postcontrast CT extravasation is associated with hematoma expansion in CTA spot negative patients.CTA斑点阴性患者的对比剂增强CT血管外渗与血肿扩大有关。
Stroke. 2009 May;40(5):1672-6. doi: 10.1161/STROKEAHA.108.541201. Epub 2009 Mar 12.
2
Hemorrhagic transformation of ischemic stroke: prediction with CT perfusion.缺血性卒中的出血性转化:CT灌注预测
Radiology. 2009 Mar;250(3):867-77. doi: 10.1148/radiol.2503080257.
3
Converting dose-length product to effective dose at CT.在CT中将剂量长度乘积转换为有效剂量。
Semi-automatic computed tomography angiography quantification assessment is an alternative method to digital subtraction angiography in intracranial stenosis: a multicenter study.
半自动计算机断层扫描血管造影定量评估是颅内狭窄中替代数字减影血管造影的一种方法:一项多中心研究。
Quant Imaging Med Surg. 2024 Jun 1;14(6):3970-3982. doi: 10.21037/qims-23-1343. Epub 2024 May 21.
4
A comparative study of low voltage, low contrast cerebral computed tomography angiography with iterative reconstruction and conventional cerebral computed tomography angiography.低电压、低对比脑 CT 血管造影与迭代重建技术和常规脑 CT 血管造影的对比研究。
Neuroradiol J. 2024 Apr;37(2):221-228. doi: 10.1177/19714009231224412. Epub 2023 Dec 26.
5
Clinical Applications of Conebeam CTP Imaging in Cerebral Disease: A Systematic Review.锥形束 CTP 成像在脑部疾病中的临床应用:系统评价。
AJNR Am J Neuroradiol. 2023 Aug;44(8):922-927. doi: 10.3174/ajnr.A7930. Epub 2023 Jul 6.
6
Infantile ischemic stroke secondary to profound arteriopathy.继发于严重动脉病变的婴儿缺血性卒中。
J Am Coll Emerg Physicians Open. 2022 Jul 5;3(4):e12768. doi: 10.1002/emp2.12768. eCollection 2022 Aug.
7
Safety of the effective radiation dose received during stroke hospitalization.中风住院期间所接受的有效辐射剂量的安全性。
J Vasc Bras. 2022 Jan 7;20:e20210142. doi: 10.1590/1677-5449.210142. eCollection 2021.
8
What is the added value of CT-angiography in patients with transient ischemic attack?CT 血管造影在短暂性脑缺血发作患者中的应用价值是什么?
BMC Neurol. 2022 Jan 3;22(1):7. doi: 10.1186/s12883-021-02523-y.
9
MR Perfusion in the Evaluation of Mechanical Thrombectomy Candidacy.磁共振灌注成像在机械取栓适应证评估中的应用。
Top Magn Reson Imaging. 2021 Aug 1;30(4):197-204. doi: 10.1097/RMR.0000000000000277.
10
A dynamic simulation framework for CT perfusion in stroke assessment built from first principles.一个基于第一原理构建的用于中风评估中CT灌注的动态模拟框架。
Med Phys. 2021 Jul;48(7):3500-3510. doi: 10.1002/mp.14887. Epub 2021 May 9.
Radiology. 2008 Sep;248(3):995-1003. doi: 10.1148/radiol.2483071964.
4
Radiation dose reduction strategy for CT protocols: successful implementation in neuroradiology section.CT 检查方案的辐射剂量降低策略:在神经放射科的成功实施
Radiology. 2008 May;247(2):499-506. doi: 10.1148/radiol.2472071054. Epub 2008 Mar 27.
5
Radiation dose, image quality, stenosis measurement, and CT densitometry using ECG-triggered coronary 64-MDCT angiography: a phantom study.使用心电图触发的冠状动脉64层螺旋CT血管造影术的辐射剂量、图像质量、狭窄测量及CT密度测定:一项体模研究
AJR Am J Roentgenol. 2008 Feb;190(2):315-20. doi: 10.2214/AJR.07.2191.
6
Postoperative cataract cases among atomic bomb survivors: radiation dose response and threshold.原子弹爆炸幸存者中的白内障术后病例:辐射剂量反应与阈值
Radiat Res. 2007 Oct;168(4):404-8. doi: 10.1667/RR0928.1.
7
Radiation dose-reduction strategies for neuroradiology CT protocols.神经放射学CT检查方案的辐射剂量降低策略。
AJNR Am J Neuroradiol. 2007 Oct;28(9):1628-32. doi: 10.3174/ajnr.A0814. Epub 2007 Sep 24.
8
The 15-Country Collaborative Study of Cancer Risk among Radiation Workers in the Nuclear Industry: estimates of radiation-related cancer risks.核工业辐射工作人员癌症风险的15国合作研究:辐射相关癌症风险评估
Radiat Res. 2007 Apr;167(4):396-416. doi: 10.1667/RR0553.1.
9
Comparison of CT perfusion and angiography and MRI in selecting stroke patients for acute treatment.CT灌注成像、血管造影及MRI在急性卒中治疗患者选择中的比较。
Neurology. 2007 Feb 27;68(9):694-7. doi: 10.1212/01.wnl.0000255959.30107.08.
10
National survey of doses from CT in the UK: 2003.英国2003年CT剂量全国调查。
Br J Radiol. 2006 Dec;79(948):968-80. doi: 10.1259/bjr/93277434.