Bailey Elizabeth E, Pfeifer Heidi H, Thiele Elizabeth A
Harvard College, Cambridge, MA, USA.
Epilepsy Behav. 2005 Feb;6(1):4-8. doi: 10.1016/j.yebeh.2004.10.006.
Fasting and other dietary regimens have been used to treat epilepsy since biblical times. The ketogenic diet, which mimics the metabolism of fasting, was used by modern physicians to treat intractable epilepsy beginning in the 1920s. With the rising popularity of drug treatments however, the ketogenic diet lost its previous status and was used in only a handful of clinics for most of the 20th century. The diet regained widespread recognition as a viable treatment option beginning in 1992 due to the efforts of parent advocate groups. Despite challenges to implementation of the treatment, the ketogenic diet has significant potential as a powerful tool for fighting epilepsy.
自圣经时代起,禁食和其他饮食疗法就被用于治疗癫痫。生酮饮食模拟禁食的代谢过程,从20世纪20年代开始,现代医生就用它来治疗难治性癫痫。然而,随着药物治疗越来越普及,生酮饮食失去了以往的地位,在20世纪的大部分时间里,只有少数诊所使用这种饮食疗法。由于家长倡导组织的努力,从1992年开始,这种饮食疗法重新获得了广泛认可,成为一种可行的治疗选择。尽管在实施这种治疗方法时存在挑战,但生酮饮食作为对抗癫痫的有力工具具有巨大潜力。