70岁以上患者的结直肠癌：预后的决定因素
Colorectal cancer in patients over 70 years of age: determinants of outcome.
作者信息
Basdanis G, Papadopoulos V N, Michalopoulos A, Fahantidis E, Apostolidis S, Berovalis P, Zatagias A, Karamanlis E
机构信息
1st Propedeutic Surgical Clinic, Aristotle University, AHEPA Hospital, Thessaloniki, Greece.
出版信息
Tech Coloproctol. 2004 Nov;8 Suppl 1:s112-5. doi: 10.1007/s10151-004-0128-7.
BACKGROUND
The aim of this study was to evaluate operative risk factors, the mortality, morbidity and survival in old patients with colorectal cancer.
METHODS
From 1160 patients with colorectal cancer, 398 patients aged 70 years or older, from 1970 to 2000, were followed-up. Dukes' classification, differentiation, sex, anatomical site and survival were compared with patients <70 years old.
RESULTS
Long-term results have been proved to be similar both in young and old patients. Relative survival rate for patients aged 70-95 (70.5%) were similar to those for patients less than 70 years old (71.6%) and also comparable between male (72.3%) and female (68%) patients.
CONCLUSIONS
Elderly patients have a lower capacity to react to postoperative complications, but the relative survival is similar to younger patients. Advanced age alone should not be used as a criterion to deny surgery for colorectal cancer.
背景
本研究旨在评估老年结直肠癌患者的手术风险因素、死亡率、发病率和生存率。
方法
对1970年至2000年间1160例结直肠癌患者中398例70岁及以上患者进行随访。将Dukes分期、分化程度、性别、解剖部位和生存率与70岁以下患者进行比较。
结果
长期结果表明，年轻患者和老年患者相似。70 - 95岁患者的相对生存率（70.5%）与70岁以下患者（71.6%）相似，男性患者（72.3%）和女性患者（68%）之间也具有可比性。
结论
老年患者对术后并发症的反应能力较低，但相对生存率与年轻患者相似。不应仅以高龄作为拒绝结直肠癌手术的标准。
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