Kanellos I, Demetriades H, Blouhos K, Tsachalis T, Pramateftakis M G, Betsis D
4th Surgical Department, Aristotle University of Thessaloniki, Greece.
Tech Coloproctol. 2004 Nov;8 Suppl 1:s119-22. doi: 10.1007/s10151-004-0130-0.
The aim of our study is to present the preliminary results of an ongoing radio-frequency (RF) ablation study in patients with hepatic metastases from colorectal cancer.
From November 2003, two patients affected with metachronous liver metastases from colorectal cancer were treated with RF ablation. The mean age of the patients was 66 years (58 and 74 years). Tumours were unifocal right-lobe lesions in one patient and bifocal in the second patient. Under general anaesthesia, a Radionics 200-W RF generator was used to ablate lesions with H2O-cooled electrodes via laparotomy. Patients' follow-up ranged from two to five months including evaluation of salient clinical, radiological and laboratory parameters.
The patients experienced moderate-to-severe pain in the right abdomen lasting for 2-3 days and mild fever for 3-6 days after treatment. During the follow-up period no local recurrence was observed.
RF ablation emerges to be a promising method for the treatment of hepatic metastases from colorectal cancer.
我们研究的目的是展示一项正在进行的针对结直肠癌肝转移患者的射频消融研究的初步结果。
从2003年11月起，两名患有结直肠癌异时性肝转移的患者接受了射频消融治疗。患者的平均年龄为66岁（分别为58岁和74岁）。一名患者的肿瘤为单发病灶，位于右叶，另一名患者的肿瘤为双发病灶。在全身麻醉下，使用Radionics 200瓦射频发生器通过剖腹术用H2O冷却电极消融病灶。患者的随访时间为2至5个月，包括对显著的临床、放射学和实验室参数的评估。
患者在治疗后右腹部出现中度至重度疼痛，持续2至3天，伴有轻度发热，持续3至6天。在随访期间未观察到局部复发。
射频消融似乎是一种治疗结直肠癌肝转移的有前景的方法。
