Yamazaki Yukiko, Jaiswal Pankaj
Center for Genetic Resource Information, National Institute of Genetics, Mishima, Shizuoka, 411-8540 Japan.
Plant Cell Physiol. 2005 Jan;46(1):63-8. doi: 10.1093/pcp/pci505. Epub 2005 Jan 19.
An enormous amount of information and materials in the field of biology has been accumulating, such as nucleotide and amino acid sequences, gene and protein functions, mutants and their phenotypes, and literature references, produced by the rapid development in this field. Effective use of the information may strongly promote biological studies, and may lead to many important findings. It is, however, time-consuming and laborious for individual researchers to collect information from individual original sites and to rearrange it for their own purpose. A concept, ontology, has been introduced in biology to support and encourage researchers to share and reuse information among biological databases. Ontology has a glossary, named dynamic controlled vocabulary, in which relationships between terms are defined. Since each term is strictly defined and identified with an ID number, a set of data represented in biological ontology is easily accessible to automated information processing, even if the data sets are across several databases and/or different organisms. In this mini-review, we introduce activities in Gramene and Oryzabase, which provide biological ontologies for Oryza sativa (rice).
随着生物学领域的快速发展,大量的信息和材料不断积累,例如核苷酸和氨基酸序列、基因和蛋白质功能、突变体及其表型以及文献参考资料等。有效利用这些信息可能会有力地推动生物学研究,并可能带来许多重要发现。然而,对于单个研究人员来说,从各个原始网站收集信息并按照自己的目的进行重新整理既耗时又费力。为了支持和鼓励研究人员在生物数据库之间共享和重用信息,生物学领域引入了一个概念——本体论。本体论有一个名为动态控制词汇表的术语表,其中定义了术语之间的关系。由于每个术语都有严格的定义并通过一个ID号进行标识,因此即使数据集分布在多个数据库和/或不同生物体中,以生物本体表示的一组数据也很容易进行自动化信息处理。在本综述中,我们介绍了Gramene和Oryzabase的相关活动,它们为水稻提供生物本体。