Vieten Daniela, Spicer Richard
Department of Paediatric Surgery, Directorate of Children's Services, Bristol Royal Hospital for Children, Paul O'Gorman Building, Upper Maudlin Street, Bristol BS2 8BJ, UK.
Semin Pediatr Surg. 2004 Nov;13(4):263-72. doi: 10.1053/j.sempedsurg.2004.10.014.
Enterocolitis remains a relatively common complication of Hirschsprung's disease with significant morbidity and mortality. The etiology of Hirschsprung's enterocolitis (HEC) is multifactorial and remains poorly understood. Preventative measures and better treatment modalities will evolve out of a better understanding of the underlying pathophysiology. Prompt recognition of HEC allows early intervention and a potential reduction in disease severity and mortality. This review of HEC describes the epidemiology, clinical and pathological features and current best practice in management. Some of the areas of research into etiology and treatment are discussed.
小肠结肠炎仍然是先天性巨结肠症相对常见的并发症，具有较高的发病率和死亡率。先天性巨结肠症小肠结肠炎（HEC）的病因是多因素的，目前仍了解甚少。对潜在病理生理学的更好理解将带来预防措施和更优治疗方式的发展。对HEC的及时识别可实现早期干预，并有可能降低疾病严重程度和死亡率。这篇关于HEC的综述描述了其流行病学、临床和病理特征以及当前最佳的管理实践。文中还讨论了病因学和治疗方面的一些研究领域。
