Riopel J, Plante M, Renaud M-C, Roy M, Têtu B
Department of Pathology, Centre Hospitalier Universitaire de Québec (CHUQ)-Pavillon L'Hôtel-Dieu de Québec, 11 Côte du Palais, Québec, Québec, Canada G1R 2J6.
Gynecol Oncol. 2005 Feb;96(2):402-6. doi: 10.1016/j.ygyno.2004.10.021.
The objective of this study was to review our experience on lymphatic dissemination in patients with low-grade endometrial stromal sarcoma.
All cases diagnosed as low-grade endometrial stromal sarcoma or endolymphatic stromal myosis before October 2003 and who had lymph node sampling at some point in their evolution were retrieved from the files of the pathology and gynecologic oncology departments of l'Hotel-Dieu de Quebec University Hospital (HDQ).
Fifteen patients with either limited lymph node biopsies or a complete lymph node dissection at some point in the course of their disease were found. Five of these patients (33%) presented lymph node metastases either at the initial hysterectomy, during a subsequent staging procedure, or at the time of a recurrence.
These findings suggest that the incidence of lymph node involvement in low-grade endometrial stromal sarcoma is higher than expected. More extensive sampling of lymph nodes in a larger number of patients may allow a better understanding of the frequency and prognostic significance of these metastases.
本研究的目的是回顾我们在低级别子宫内膜间质肉瘤患者淋巴扩散方面的经验。
从魁北克大学医院迪厄酒店分院（HDQ）病理科和妇科肿瘤学部门的档案中检索出所有在2003年10月之前被诊断为低级别子宫内膜间质肉瘤或淋巴管内间质肌病且在病程中的某个时间点进行了淋巴结取样的病例。
发现15例患者在病程中的某个时间点进行了有限的淋巴结活检或完整的淋巴结清扫。其中5例患者（33%）在初次子宫切除时、随后的分期手术期间或复发时出现了淋巴结转移。
这些发现表明，低级别子宫内膜间质肉瘤患者淋巴结受累的发生率高于预期。对更多患者进行更广泛的淋巴结取样可能有助于更好地了解这些转移的频率和预后意义。
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