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细胞生物学中的振荡

Oscillations in cell biology.

作者信息

Kruse Karsten, Jülicher Frank

机构信息

Max Planck Institut für Physik komplexer Systeme, Nöthnitzer Str. 38, 01187 Dresden, Germany.

出版信息

Curr Opin Cell Biol. 2005 Feb;17(1):20-6. doi: 10.1016/j.ceb.2004.12.007.

Abstract

Oscillations play an important role in many dynamic cellular processes. They can emerge as the collective dynamic behavior of an ensemble of interacting components in the cell. Examples include oscillations in cytoskeletal structures such as the axonemes of cilia. Spontaneous oscillations of mechano-sensitive hair bundles have been shown to give frequency selectivity and amplification to mechano-sensation. In some bacteria, oscillations of Min proteins are important for division site selection. Genetic oscillators form the basis of circadian clocks. All these oscillations share many general features. Models and theoretical approaches are essential for an understanding of the principles underlying these dynamic cellular processes.

摘要

振荡在许多动态细胞过程中发挥着重要作用。它们可以作为细胞中相互作用的一组组件的集体动态行为而出现。例子包括细胞骨架结构中的振荡,如纤毛的轴丝。机械敏感毛束的自发振荡已被证明能赋予机械感觉频率选择性和放大作用。在一些细菌中,Min蛋白的振荡对于分裂位点的选择很重要。遗传振荡器构成了生物钟的基础。所有这些振荡都有许多共同特征。模型和理论方法对于理解这些动态细胞过程背后的原理至关重要。

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