Kettenbach Joachim, Helbich Thomas H, Huber Sabine, Zuna Ivan, Dock Wolfgang
Department of Radiology, University Hospital of Vienna, Waehringer Guertel 18-20, A-1090 Vienna, Austria.
Eur J Radiol. 2005 Feb;53(2):238-44. doi: 10.1016/j.ejrad.2004.04.017.
To objectively quantify the effects of a microbubble contrast agent to differentiate breast tumors with power doppler ultrasound and to compare these results with color doppler ultrasound (CD US).
In 47 patients a microbubble contrast agent was injected intravenously. Computer-assisted quantitative assessment of the color pixel density was performed to evaluate the increase in Doppler signals. Results were compared to previously published results of a color Doppler ultrasound study.
Peak color pixel density at contrast-enhanced power Doppler ultrasound was higher for carcinomas than for benign tumors (P < 0.03). Time to peak enhancement was shorter in carcinomas than in benign tumors (P < 0.01). For both parameters, diagnostic accuracy of power Doppler ultrasound was 69 and 78%, and for color Doppler ultrasound 62 and 76%, respectively.
Quantitative assessment of contrast-enhanced power Doppler ultrasound showed significant differences in malignant and benign breast tumors. Diagnostic accuracy of contrast-enhanced power Doppler ultrasound was higher compared to color Doppler ultrasound.
客观量化微泡造影剂在功率多普勒超声下鉴别乳腺肿瘤的效果，并将这些结果与彩色多普勒超声（CD US）进行比较。
对47例患者静脉注射微泡造影剂。采用计算机辅助定量评估彩色像素密度，以评估多普勒信号的增加情况。将结果与先前发表的彩色多普勒超声研究结果进行比较。
在造影增强功率多普勒超声下，癌组织的峰值彩色像素密度高于良性肿瘤（P < 0.03）。癌组织的增强达峰时间短于良性肿瘤（P < 0.01）。对于这两个参数，功率多普勒超声的诊断准确率分别为69%和78%，彩色多普勒超声的诊断准确率分别为62%和76%。
造影增强功率多普勒超声的定量评估显示恶性和良性乳腺肿瘤存在显著差异。与彩色多普勒超声相比，造影增强功率多普勒超声的诊断准确率更高。
