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使用生物可吸收植入物治疗桡骨远端骨折的稳定性:英国患者的观点。

Use of bio-resorbable implants for stabilisation of distal radius fractures: the United Kingdom patients' perspective.

作者信息

Mittal R, Morley J, Dinopoulos H, Drakoulakis E G, Vermani E, Giannoudis P V

机构信息

Department of Trauma and Orthopaedic Surgery, St. James's University Hospital, Leeds LS9 7TF, UK.

出版信息

Injury. 2005 Feb;36(2):333-8. doi: 10.1016/j.injury.2004.09.015.

Abstract

Bio-resorbable implants have been, recently, introduced in the United Kingdom. To our knowledge there have been no randomised studies to assess perception of today's well-informed patients about this new method of fracture stabilisation. In order to assess the patients' perception a prospective study was performed on 100 consecutive adult patients with distal radius fractures. Following detailed verbal and written information about both resorbable and metal implants, the patients were asked to complete a specifically designed questionnaire. Ninety-five percent of the patients appreciated the 'resorbable' feature and responded that they would prefer to have their fracture stabilised with a resorbable implant. Conversely, 91% of the participants considered removal as the most negative aspect of the metal implant (p<0.0001). While 56% of the patients felt that it was relatively a new and evolving technology, 29% of them had apprehension about the relative strength of the resorbable implant. Eighty percent of the patients stated that they would be happy to participate in clinical trials to compare the use of bio-resorbable implants versus metal ones (p=0.0001). This study sets the foundation for the implementation of prospective randomised trials to assess the efficacy of the new generation of bio-resorbable implants.

摘要

生物可吸收植入物最近已在英国投入使用。据我们所知,尚无随机研究来评估当今信息充分的患者对这种新型骨折固定方法的看法。为了评估患者的看法,我们对100例连续的桡骨远端骨折成年患者进行了一项前瞻性研究。在提供了关于可吸收植入物和金属植入物的详细口头和书面信息后,要求患者完成一份专门设计的问卷。95%的患者赞赏“可吸收”这一特性,并表示他们更愿意使用可吸收植入物来固定骨折。相反,91%的参与者认为取出金属植入物是最不利的方面(p<0.0001)。虽然56%的患者认为这是一项相对较新且不断发展的技术,但其中29%的患者对可吸收植入物的相对强度感到担忧。80%的患者表示他们愿意参加临床试验,以比较生物可吸收植入物与金属植入物的使用情况(p=0.0001)。这项研究为开展前瞻性随机试验以评估新一代生物可吸收植入物的疗效奠定了基础。

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