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宫内节育器对仓鼠子宫氨基葡聚糖的某些影响。

Some effects of an intrauterine device on glucosaminoglycans of the hamster uterus.

作者信息

Moore P J, Rosenquist T H

出版信息

Fertil Steril. 1979 Jul;32(1):120-4. doi: 10.1016/s0015-0282(16)44127-0.

DOI:10.1016/s0015-0282(16)44127-0
PMID:156649
Abstract

The effect of an intrauterine device (IUD) on non-heparin sulfomucopolysaccharide (SMP) was studied in castrated, hormone-treated, and cycling hamsters by photographic densitometry of tissue sections stained specifically for SMP with Alcian blue. Non-heparin SMP increased slightly in the myometrium of IUD-containing uteri of all castrated groups, with the increase being significant in only the peanut oil-treated group. The endometrium also showed slight increases in sulfomucin in IUD-containing uteri of peanut oil, progesterone, and estrogen plus progesterone-treated animals. These increases, however, were not statistically significant. In cycling hamsters the IUD had little effect on uterine non-heparin SMP in most cycle stages.

摘要

通过对用阿尔辛蓝特异性染色的组织切片进行光密度测定,研究了宫内节育器(IUD)对去势、激素处理和处于发情周期的仓鼠体内非肝素硫酸黏多糖(SMP)的影响。在所有去势组中,含IUD子宫的子宫肌层中,非肝素SMP略有增加,仅在花生油处理组中增加显著。在花生油、孕酮以及雌激素加孕酮处理的动物中,含IUD子宫的子宫内膜中硫黏蛋白也略有增加。然而,这些增加在统计学上并不显著。在处于发情周期的仓鼠中,IUD在大多数周期阶段对子宫非肝素SMP几乎没有影响。

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