宫内节育器对仓鼠子宫肥大细胞数量及分布的影响。

The effect of an intrauterine device on mast cell numbers and distribution in the hamster uterus.

作者信息

Moore P J, Velky P, Rosenquist T H

出版信息

Res Exp Med (Berl). 1979 Jul 20;175(3):223-32. doi: 10.1007/BF01851278.

Abstract

The effect of an IUD on mast cell numbers and distribution in the uterus was studied in castrated, castrated hormone-treated and cycling hamsters. The device had a stimulatory effect on total mast cell numbers in those animals that received no treatment, peanut oil, or estrogen therapy and in all cycling animals. The device also apparently causes mast cells to be redistributed in the different areas of the uterus. The results indicate that the IUD alters the uterine mast cell response to exogenous hormones and cycle times.

摘要

在去势、去势激素处理和处于发情周期的仓鼠中，研究了宫内节育器（IUD）对子宫中肥大细胞数量和分布的影响。该装置对未接受任何处理、接受花生油或雌激素治疗的动物以及所有处于发情周期的动物的肥大细胞总数有刺激作用。该装置显然还会使肥大细胞在子宫的不同区域重新分布。结果表明，宫内节育器改变了子宫肥大细胞对外源激素和发情周期时间的反应。