不同的巴西利什曼原虫分离株诱导趋化因子表达模式的不同变化速度。
Distinct Leishmania braziliensis isolates induce different paces of chemokine expression patterns.
作者信息
Teixeira Maria Jania, Fernandes Juliana Dumet, Teixeira Clarissa Romero, Andrade Bruno Bezerril, Pompeu Margarida Lima, Santana da Silva João, Brodskyn Cláudia Ida, Barral-Netto Manoel, Barral Aldina
机构信息
Centro de Pesquisas Gonçalo Moniz-Fiocruz-BA, 121 Rua Waldemar Falcão, Salvador, Bahia, Brazil 40295-001.
出版信息
Infect Immun. 2005 Feb;73(2):1191-5. doi: 10.1128/IAI.73.2.1191-1195.2005.
Abstract
Inflammatory events during Leishmania braziliensis infection in mice were investigated. Large lesions were directly correlated with the inflammatory reaction but not with parasite burden. Different L. braziliensis strains induce different paces of chemokine expression patterns, leading to diverse cell recruitment and differential inflammatory responses.
摘要
对巴西利什曼原虫感染小鼠期间的炎症事件进行了研究。大的病变与炎症反应直接相关，但与寄生虫负荷无关。不同的巴西利什曼原虫菌株诱导趋化因子表达模式的不同速度，导致不同的细胞募集和不同的炎症反应。
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