Mitsunari Masahiro, Yoshida Souichi, Deura Imari, Horie Sayako, Tsukihara Satoru, Harada Tasuku, Irie Takashi, Terakawa Naoki
Department of Obstetrics and Gynecology, Tottori University School of Medicine, Yonago, Japan.
J Obstet Gynaecol Res. 2005 Feb;31(1):16-21. doi: 10.1111/j.1447-0756.2005.00246.x.
We examined whether the detection of Ureaplasma urealyticum DNA in the cervix is associated with preterm labor and delivery.
Eighty-two women (23 preterm labor cases and 59 controls) with no evidence of prophlogistic microorganisms on routine microbiologic examination were enrolled for this study. U. urealyticum colonization was examined using polymerase chain reaction of cervical swabs.
The positivity rate of U. urealyticum DNA in preterm labor cases was significantly higher than that in the controls (87.0%vs 45.8%, P=0.0007). Women in the U. urealyticum-positive group more frequently delivered preterm compared with those in the negative group (36.2%vs 11.4%, P=0.0111). In five cases that delivered preterm with histologically confirmed chorioamnionitis, U. urealyticum DNA was detected in the placenta.
Cervical U. urealyticum colonization might be associated with preterm labor and delivery.
我们研究了宫颈解脲脲原体DNA的检测是否与早产及分娩有关。
本研究纳入了82名女性（23例早产病例和59例对照），她们在常规微生物学检查中未发现炎性微生物迹象。使用宫颈拭子的聚合酶链反应检测解脲脲原体定植情况。
早产病例中解脲脲原体DNA的阳性率显著高于对照组（87.0%对45.8%，P = 0.0007）。与阴性组相比，解脲脲原体阳性组的女性早产频率更高（36.2%对11.4%，P = 0.0111）。在5例经组织学证实为绒毛膜羊膜炎的早产病例中，在胎盘中检测到了解脲脲原体DNA。
宫颈解脲脲原体定植可能与早产及分娩有关。
