Agar Nita, Freeman Susanne
Skin and Cancer Foundation, Sydney, New South Wales, Australia.
Australas J Dermatol. 2005 Feb;46(1):15-7. doi: 10.1111/j.1440-0960.2005.00129.x.
A 10-year-old girl presented with a 2-year history of severe cheilitis. Despite cessation of any lip-licking behaviour her symptoms continued to worsen, with only minimum relief from therapeutic measures. Patch testing proved strongly positive to cocamidopropyl betaine, which was noted to be present in the patient's '2-in-1 toothpaste and mouthwash'. Her cheilitis settled after avoidance of this product. Cocamidopropyl betaine, a surfactant, is a common allergen in hairdressers; however, this case highlights the importance of excluding a contact allergy to this product in patients with intractable cheilitis.
一名10岁女孩有2年严重唇炎病史。尽管停止了任何舔唇行为，但其症状仍持续恶化，治疗措施仅带来轻微缓解。斑贴试验结果显示对椰油酰胺丙基甜菜碱呈强阳性，该成分存在于患者使用的“二合一牙膏和漱口水”中。停用该产品后，她的唇炎症状得到缓解。椰油酰胺丙基甜菜碱作为一种表面活性剂，是美发师中常见的过敏原；然而，该病例凸显了在患有顽固性唇炎的患者中排除对该产品接触性过敏的重要性。
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