Fowler J F
Department of Medicine, University of Louisville, Kentucky.
Cutis. 1993 Nov;52(5):281-4.
Cocamidopropyl betaine is a surfactant coming into wide use in shampoos and other cleansing products. Recent reports have implicated it as a potential allergen, although it is less irritating than other surfactants such as sodium lauryl sulfate. Twelve positive patch test results were seen over a period of fifteen months of testing in selected patients. Of these, seven results were thought to be relevant. All seven patients with relevant reactions and four of the five with uncertain relevance had dermatitis of the head and neck area. It is concluded that although cocamidopropyl betaine is not a common allergen, it may be at least partially responsible for some cases of allergic dermatitis of the head and neck.
椰油酰胺丙基甜菜碱是一种在洗发水和其他清洁产品中广泛使用的表面活性剂。最近的报告表明它可能是一种潜在的过敏原，尽管它比其他表面活性剂如十二烷基硫酸钠刺激性小。在对选定患者进行的15个月测试期间，观察到12例阳性斑贴试验结果。其中，7例结果被认为是相关的。所有7例有相关反应的患者以及5例相关性不确定的患者中的4例都有头颈部皮炎。结论是，虽然椰油酰胺丙基甜菜碱不是常见的过敏原，但它可能至少部分导致了一些头颈部过敏性皮炎病例。
