Lok C A R, Zürcher A F, van der Velden J
Academic Medical Center, Department of Obstetrics and Gynecology (H4-Zuid), PO Box 22660, 1100 DD Amsterdam, The Netherlands.
Int J Gynecol Cancer. 2005 Jan-Feb;15(1):163-6. doi: 10.1111/j.1048-891X.2005.14433.x.
A case of a 56-year-old woman with a mole pregnancy and a human chorionic gonadotropin (HCG)-induced thyreotoxicosis is presented. A proper diagnosis was only made after a period of patient and doctor's delay. After performing a hysterectomy, the HCG quickly normalized. Thyroid function normalized with thiamazol treatment. It is well known that older women have a higher risk to develop gestational trophoblastic disease (GTD). Furthermore, the chance of persistent trophoblastic disease is increased in this population. The literature on risk factors for developing persistent GTD and the possibilities for treatment in older patients is reviewed.
本文报告一例56岁患有葡萄胎妊娠及人绒毛膜促性腺激素（HCG）诱发甲状腺毒症的女性病例。经过一段时间患者和医生的延误后才做出正确诊断。行子宫切除术后，HCG迅速恢复正常。使用甲巯咪唑治疗后甲状腺功能恢复正常。众所周知，老年女性发生妊娠滋养细胞疾病（GTD）的风险更高。此外，该人群持续性滋养细胞疾病的几率增加。本文对老年患者发生持续性GTD的危险因素及治疗可能性的文献进行了综述。
