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巨大侵袭性葡萄胎表现为围绝经期女性腹盆腔肿物的病因:一种罕见病理的不寻常表现

Giant invasive mole presenting as a cause of abdominopelvic mass in a perimenopausal woman: An unusual presentation of a rare pathology.

作者信息

Akyol Alpaslan, Şimşek Memet, Üçer Özlem

机构信息

Department of Obstetrics and Gynecology, Firat University Faculty of Medicine, Elazig, Turkey.

Department of Pathology, Firat University Faculty of Medicine, Elazig, Turkey.

出版信息

Obstet Gynecol Sci. 2016 Nov;59(6):548-553. doi: 10.5468/ogs.2016.59.6.548. Epub 2016 Nov 15.

DOI:10.5468/ogs.2016.59.6.548
PMID:27896261
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5120078/
Abstract

Invasive mole is a benign gestational trophoblastic disease that arises from the myometrial invasion of any gestational event via direct extension through tissue or vascular structures. Invasive mole (and other gestational trophoblastic diseases) may present with life-threatening complications including uterine perforation, excessive bleeding, acute hemoperitoneum, and abdominal pain. We report a case of invasive mole presenting as abdominal distention in a 51-year-old perimenopausal woman (gravida 12, para 12, abortion 0). The patient was admitted to the gynecology clinic with a giant uterine mass filling the pelvic and abdominal cavity. To our knowledge, this is the first case in the literature of a gestational trophoblastic neoplasia presenting with uterine mass of 28 weeks' gestational size in this age group. Interestingly, complications such as uterine rupture or invasion of the adjacent structures (such as parametrial tissues or blood vessels) had not developed in our patient despite the considerable enlargement of the uterus.

摘要

侵蚀性葡萄胎是一种良性妊娠滋养细胞疾病,它通过组织或血管结构直接蔓延,由任何妊娠事件的肌层浸润引起。侵蚀性葡萄胎(以及其他妊娠滋养细胞疾病)可能出现危及生命的并发症,包括子宫穿孔、大量出血、急性腹腔积血和腹痛。我们报告一例51岁围绝经期妇女(孕12产12,流产0次)以腹胀为表现的侵蚀性葡萄胎病例。该患者因巨大子宫肿物充满盆腔和腹腔而入住妇科门诊。据我们所知,这是文献中该年龄组首例以妊娠28周大小子宫肿物为表现的妊娠滋养细胞肿瘤。有趣的是,尽管子宫显著增大,但我们的患者并未发生子宫破裂或邻近结构(如宫旁组织或血管)浸润等并发症。

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本文引用的文献

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Invasive mole in a perimenopausal woman: a case report and systematic review.一名围绝经期妇女的侵袭性葡萄胎:病例报告及系统评价
Arch Gynecol Obstet. 2015 Dec;292(6):1193-9. doi: 10.1007/s00404-015-3777-z. Epub 2015 Jun 7.
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Multicenter analysis of gestational trophoblastic neoplasia in Turkey.土耳其妊娠滋养细胞肿瘤的多中心分析。
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Uterine rupture due to invasive metastatic gestational trophoblastic neoplasm.因侵袭性转移性妊娠滋养细胞肿瘤导致的子宫破裂。
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Perimenopausal giant hydatidiform mole complicated with preeclampsia and hyperthyroidism: A case report and literature review.围绝经期巨大葡萄胎合并子痫前期和甲状腺功能亢进症:一例报告及文献复习
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