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盆腔孤立性纤维瘤伴低血糖:一例报告

Solitary fibrous tumor in the pelvic cavity with hypoglycemia: report of a case.

作者信息

Nagase Takeshi, Adachi Iwao, Yamada Tetsuji, Murakami Nozomu, Morita Katsuya, Yoshino Yuji, Katayanagi Kazuyoshi, Kurumaya Hiroshi

机构信息

Department of General and Gastrointestinal Surgery, Ishikawa Prefectural Central Hospital, 2-1 Kuragetsu Higashi, Kanazawa 920-8530, Japan.

出版信息

Surg Today. 2005;35(2):181-4. doi: 10.1007/s00595-004-2877-3.

Abstract

A case of solitary fibrous tumor (SFT) in the pelvic cavity with hypoglycemia is reported. The patient was a 60-year-old man who was referred to our hospital for a closer examination of hypoglycemia. Computed tomography demonstrated a mass, measuring 14 x 9 cm in size, in the pelvic cavity. Magnetic resonance imaging showed the mass to have a low signal intensity on T1-weighted images and a high intensity on T2-weighted images. Laparotomy revealed no peritoneal dissemination nor lymph node metastasis. An en bloc excision of the tumor was performed with a good recovery, and the hypoglycemia disappeared. Histologically, the tumor was composed of spindle-shaped and oval cells in sarcoma, based on a moderate mitotic rate and cellularity. Immunohistochemically, the tumor was positive for CD34 and negative for keratin, alpha-smooth muscle actin, desmin, S100 protein, c-kit protein, and epithelial membrane antigen. Based on these findings, the tumor was diagnosed to be malignant SFT in the pelvic cavity.

摘要

报告了一例盆腔孤立性纤维瘤(SFT)伴低血糖的病例。患者为一名60岁男性,因对低血糖进行进一步检查而转诊至我院。计算机断层扫描显示盆腔内有一个大小为14×9 cm的肿块。磁共振成像显示该肿块在T1加权图像上呈低信号强度,在T2加权图像上呈高信号强度。剖腹手术显示无腹膜播散及淋巴结转移。对肿瘤进行了整块切除,恢复良好,低血糖消失。组织学上,肿瘤由肉瘤中的梭形和椭圆形细胞组成,有中度的有丝分裂率和细胞密度。免疫组织化学检查显示,肿瘤CD34阳性,角蛋白、α平滑肌肌动蛋白、结蛋白、S100蛋白、c-kit蛋白和上皮膜抗原阴性。基于这些发现,该肿瘤被诊断为盆腔恶性SFT。

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