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盆腔孤立性纤维瘤:一种罕见的软组织肿瘤。病例报告。

Solitary fibrous tumor of the pelvis: an uncommon soft-tissue tumor. A case report.

作者信息

Pata Francesco, Orsini Vincenzo, Lucisano Ada Maria, Pafundi Donato Paolo, Sacco Rosario

机构信息

Department of General Surgery, Magna Graecia University of Catanzaro, Germaneto, 88100 Catanzaro, Italy.

出版信息

Ann Ital Chir. 2010 Nov-Dec;81(6):457-60.

Abstract

A rare case of Solitary fibrous tumor (SFT) of the pelvis is reported. A 76-years-old man presented with a low abdominal pain, acute urine retention and constipation. Imaging studies (US, CT MR) showed an 17 x 10 x 9 ovoid mass in the pelvis, dislocating bladder and rectum. Finally, trans-rectal needle biopsy suggested the diagnosis of SFT. En bloc excision of tumor and rectum (because of strong adhesions) was performed. Histological examination showed spindle and fibroblastic-like cells dispersed in collagenous areas with positive stains for CD34, bcl-2, CD99 and it confirmed diagnosis of SFT. No postoperative complications occurred, only vesico-sphincter dyssynergia was found by urodynamics. After 5 years, patient is disease-free. SFT is, usually, benign tumor with slow growth and excellent prognosis. Complete surgical resection is the only curative treatment. However, 10-15% of SFT are malignant and histological findings cannot always predict clinical behaviour. For this reason, careful and long term follow-up is necessary after surgery.

摘要

本文报道了一例罕见的盆腔孤立性纤维瘤(SFT)病例。一名76岁男性患者出现下腹部疼痛、急性尿潴留和便秘。影像学检查(超声、CT、磁共振成像)显示盆腔内有一个17×10×9厘米的椭圆形肿块,使膀胱和直肠移位。最终,经直肠穿刺活检提示为SFT。由于粘连严重,对肿瘤和直肠进行了整块切除。组织学检查显示梭形和成纤维细胞样细胞散在于胶原区域,CD34、bcl-2、CD99染色呈阳性,确诊为SFT。术后未发生并发症,尿动力学检查仅发现膀胱括约肌协同失调。5年后,患者无病生存。SFT通常是一种生长缓慢、预后良好的良性肿瘤。完整的手术切除是唯一的治愈性治疗方法。然而,10% - 15%的SFT是恶性的,组织学表现并不总能预测临床行为。因此,术后需要进行仔细且长期的随访。

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