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人工瓣膜心内膜炎:外科手术及临床结果

Prosthetic valve endocarditis: surgical procedures and clinical outcome.

作者信息

Otaki M

机构信息

Department of Surgery, Osaka National Hospital, Japan.

出版信息

Cardiovasc Surg. 1994 Apr;2(2):212-5.

PMID:8049948
Abstract

Over a period of 10 years, 25 patients underwent reoperation for prosthetic valve endocarditis. The basic procedure for surgical treatment differed depending on the presence or absence of annular ring abscess. Standard valve replacement was employed in 15 patients without annular ring abscess (three aortic, eleven mitral and one tricuspid). The ten other patients who had had partial destruction of the annulus underwent complex surgical treatment (six aortic, three mitral and one aortic and mitral). Complex operative techniques consisted of three different procedures, depending on the anatomical lesion in each patient. Aortic valve replacement was performed by subannular implantation with horizontal Dacron felt-supported mattress sutures through the ventricular septum, ventricular outflow wall muscles and base of the anterior mitral leaflet. A prosthesis with a polytetrafluoroethylene flange was used for mitral valve replacement to permit double suturing of the prosthesis and firm anchoring. Double valve replacement (mitral, aortic) with destruction of the fibrous skeleton was carried out using a composite graft consisting of a triangular-shaped Dacron patch and two Björk-Shiley valves. There were four operative deaths (16%; three who underwent standard valve replacement and one who had complex surgical treatment). In no case could the cause of death be related to the surgical procedure. These patients had had haemodynamic decompensation before operation and required urgent reoperation. Preoperative New York Heart Association functional class IV (P < 0.05) and operative urgency (P < 0.05) had a significant correlation with mortality. On the basis of these results, operative mortality can be improved if conditions leading to myocardial damage are prevented and proper reconstruction conducted.

摘要

在10年期间,25例患者因人工瓣膜心内膜炎接受了再次手术。手术治疗的基本程序因是否存在瓣环脓肿而有所不同。15例无瓣环脓肿的患者采用了标准瓣膜置换术(3例主动脉瓣、11例二尖瓣和1例三尖瓣)。另外10例瓣环部分破坏的患者接受了复杂的手术治疗(6例主动脉瓣、3例二尖瓣和1例主动脉瓣合并二尖瓣)。复杂的手术技术包括三种不同的手术方法,具体取决于每位患者的解剖病变情况。主动脉瓣置换术通过在室间隔、心室流出道壁肌肉和二尖瓣前叶基部水平植入带涤纶毡支撑的褥式缝线进行瓣下植入。二尖瓣置换术使用带有聚四氟乙烯凸缘的假体,以便对假体进行双重缝合并牢固固定。对于纤维骨架破坏的二尖瓣和主动脉瓣双瓣膜置换术,采用由三角形涤纶补片和两个 Björk-Shiley 瓣膜组成的复合移植物进行。有4例手术死亡(16%;3例接受标准瓣膜置换术,1例接受复杂手术治疗)。在任何情况下,死亡原因均与手术操作无关。这些患者术前存在血流动力学失代偿,需要紧急再次手术。术前纽约心脏协会功能分级为IV级(P < 0.05)和手术紧迫性(P < 0.05)与死亡率有显著相关性。基于这些结果,如果能够预防导致心肌损伤的情况并进行适当的重建,手术死亡率可以得到改善。

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