Sahin Nurettin
Mugla University, Egitim Fakultesi, Biyoloji Egitimi Anabilim Dali, TR-48170 Kotekli, Mugla, Turkey.
J Basic Microbiol. 2005;45(1):64-71. doi: 10.1002/jobm.200410427.
Bacterial blotch caused by Pseudomonas tolaasii is still one of the main diseases in mushroom farms. Effective treatment of the infections caused by P. tolaasii is yet to be established. The isolation and identification of three Streptomyces species that showed antimicrobial activity against P. tolaasii NCPPB 2192(T) were described. Six strains were highly active with an inhibition zone more than 20 mm in diameter. They were assigned to the known Streptomyces cluster groups as S. rochei, S. lydicus and S. antibioticus. The fermentation, preliminary extraction and isolation of bioactive components were carried out. The bioactive compound may be a beta-lactam structurally related to the penicillins.
由托拉斯假单胞菌引起的细菌性斑点病仍是蘑菇种植场的主要病害之一。针对托拉斯假单胞菌引起的感染，尚未确立有效的治疗方法。本文描述了对托拉斯假单胞菌NCPPB 2192(T)具有抗菌活性的三种链霉菌的分离和鉴定。六株菌株活性很高，抑菌圈直径超过20毫米。它们被归入已知的链霉菌聚类组，分别为罗氏链霉菌、利迪链霉菌和抗生链霉菌。对生物活性成分进行了发酵、初步提取和分离。该生物活性化合物可能是一种结构上与青霉素相关的β-内酰胺。
