Clegg J, Hollis C, Mawhood L, Rutter M
University of Sheffield, UK.
J Child Psychol Psychiatry. 2005 Feb;46(2):128-49. doi: 10.1111/j.1469-7610.2004.00342.x.
Little is known on the adult outcome and longitudinal trajectory of childhood developmental language disorders (DLD) and on the prognostic predictors.
Seventeen men with a severe receptive DLD in childhood, reassessed in middle childhood and early adult life, were studied again in their mid-thirties with tests of intelligence (IQ), language, literacy, theory of mind and memory together with assessments of psychosocial outcome. They were compared with the non language disordered siblings of the DLD cohort to control for shared family background, adults matched to the DLD cohort on age and performance IQ (IQM group) and a cohort from the National Child Development Study (NCDS) matched to the DLD cohort on childhood IQ and social class.
The DLD men had normal intelligence with higher performance IQ than verbal IQ, a severe and persisting language disorder, severe literacy impairments and significant deficits in theory of mind and phonological processing. Within the DLD cohort higher childhood intelligence and language were associated with superior cognitive and language ability at final adult outcome. In their mid-thirties, the DLD cohort had significantly worse social adaptation (with prolonged unemployment and a paucity of close friendships and love relationships) compared with both their siblings and NCDS controls. Self-reports showed a higher rate of schizotypal features but not affective disorder. Four DLD adults had serious mental health problems (two had developed schizophrenia).
A receptive developmental language disorder involves significant deficits in theory of mind, verbal short-term memory and phonological processing, together with substantial social adaptation difficulties and increased risk of psychiatric disorder in adult life. The theoretical and clinical implications of the findings are discussed.
关于儿童发育性语言障碍(DLD)的成人结局、纵向发展轨迹以及预后预测因素,人们所知甚少。
对17名童年时期患有严重接受性DLD的男性进行研究,他们在童年中期和成年早期接受了重新评估,并在三十多岁时再次接受智力(IQ)、语言、读写能力、心理理论和记忆测试,同时进行社会心理结局评估。将他们与DLD队列中无语言障碍的兄弟姐妹进行比较,以控制共同的家庭背景;与在年龄和表现智商(IQM组)上与DLD队列匹配的成年人进行比较;还与全国儿童发展研究(NCDS)中在童年智商和社会阶层上与DLD队列匹配的队列进行比较。
患有DLD的男性智力正常,表现智商高于言语智商,存在严重且持续的语言障碍、严重的读写能力受损,以及心理理论和语音处理方面的显著缺陷。在DLD队列中,童年时期较高的智力和语言水平与成年最终结局时较好的认知和语言能力相关。与他们的兄弟姐妹和NCDS对照组相比,在三十多岁时,DLD队列的社会适应能力明显更差(失业时间延长,亲密友谊和恋爱关系匮乏)。自我报告显示,具有分裂型特征的比例较高,但情感障碍比例不高。4名患有DLD的成年人存在严重的心理健康问题(2人发展为精神分裂症)。
接受性发育性语言障碍涉及心理理论、言语短期记忆和语音处理方面的显著缺陷,同时伴有大量社会适应困难以及成年后患精神疾病的风险增加。文中讨论了这些发现的理论和临床意义。