Mouridsen Svend Erik, Hauschild Karen-Marie
Department of Child and Adolescent Psychiatry, Bispebjerg University Hospital, DK-2400, Copenhagen, Denmark.
Logoped Phoniatr Vocol. 2009;34(3):135-41. doi: 10.1080/14015430903117441.
Traditionally developmental language disorders (DLDs) have been studied with focus on psycholinguistic and cognitive implications, and little is known of the long-term psychosocial outcomes of individuals diagnosed with a DLD as children. The objective of this study was to compare the prevalence rates and types of personality disorders (PDs) in a clinical sample of 469 individuals diagnosed as children with DLD, with PDs in 2,345 matched controls from the general population without a known history of DLD, using data from the nation-wide Danish Psychiatric Central Register (DPCR). The average observation time was 34.7 years, and mean age at follow-up was 35.8 years. Of the 469 individuals with DLD, 23 (4.9%) were known in DPCR with a PD diagnosis, compared with 51/2,345 (2.2%) in the control group (P =0.0007). Variables at assessment in childhood (gender, IQ, presence of a receptive language disorder, and degree of receptive and expressive language disorder) were not associated with a PD diagnosis in the DPCR at follow-up. Our results provide additional support to the notion that DLD is a marker of increased vulnerability to the development of a PD in adulthood and emphasizes that more research is needed to understand the links between a diagnosis of DLD in childhood and a PD in adult years.
传统上，对发育性语言障碍（DLD）的研究主要集中在心理语言学和认知方面，而对于儿童时期被诊断为患有DLD的个体的长期心理社会后果知之甚少。本研究的目的是利用丹麦全国精神病学中央登记处（DPCR）的数据，比较469名儿童时期被诊断为患有DLD的个体临床样本中的人格障碍（PD）患病率和类型，与2345名来自普通人群且无DLD病史的匹配对照中的PD患病率和类型。平均观察时间为34.7年，随访时的平均年龄为35.8岁。在469名患有DLD的个体中，有23人（4.9%）在DPCR中被诊断为患有PD，而对照组中这一比例为51/2345（2.2%）（P = 0.0007）。儿童期评估时的变量（性别、智商、接受性语言障碍的存在情况以及接受性和表达性语言障碍的程度）与随访时DPCR中的PD诊断无关。我们的结果为DLD是成年后患PD易感性增加的一个标志这一观点提供了额外支持，并强调需要更多研究来理解儿童期DLD诊断与成年期PD之间的联系。
