Hayashi S, Toyoshima H, Miyanishi K, Tanabe N, Funazaki T, Obata A, Kamimura K
Department of Public Health, Niigata University School of Medicine.
Nihon Koshu Eisei Zasshi. 1992 Feb;39(2):83-9.
Characteristics of the circadian variation for sudden death (SD), were studied by analyzing summary death certificates for the period of 1984 to 1986 in Niigata prefecture. SD was defined as death within 2 hours of onset of underlying cause (n = 4,362), and the time of onset of the cause was determined by subtracting the "time elapsed until death" from the "time of death." The periodicity for time of onset of the cause was analyzed in groups stratified by year, season, sex and age with Rogers' method utilized to check the statistical significance of the periodicity. SD, as a whole, showed a statistically significant circadian variation with a low incidence during 0 to 4 A.M. and a high incidence during 6 to 8 A.M. and 6 to 8 P.M. By season, no significant circadian variation was seen in the summer unlike for other seasons. When analyzed by age group, no significant circadian variation in SD was seen for the young to middle aged group (15-54 years old). On the other hand, there was a significant circadian variation for the senior (55 to 74 years old) and the elderly group (75 years old or older) with a low incidence during 0 to 4 A.M. and high incidence during 6 to 12 A.M. and 6 to 8 P.M.. For the old age group, the number of the cases increased so remarkably as to form an evening peak. The percentage of SD for young to middle cases was higher in the summer than in the other seasons which may be the reason for absence of significant circadian variation in the summer.
通过分析新潟县1984年至1986年期间的死亡证明汇总，研究了猝死（SD）的昼夜变化特征。SD被定义为潜在病因发作后2小时内死亡（n = 4362），病因发作时间通过从“死亡时间”中减去“直到死亡的 elapsed时间”来确定。采用罗杰斯方法，对按年份、季节、性别和年龄分层的组中病因发作时间的周期性进行分析，以检验周期性的统计学显著性。总体而言，SD呈现出具有统计学意义的昼夜变化，凌晨0点至4点发病率低，上午6点至8点和下午6点至8点发病率高。按季节划分，与其他季节不同，夏季未观察到显著的昼夜变化。按年龄组分析时，青年至中年组（15 - 54岁）的SD未观察到显著的昼夜变化。另一方面，老年组（55至74岁）和高龄组（75岁及以上）存在显著的昼夜变化，凌晨0点至4点发病率低，上午6点至12点和下午6点至8点发病率高。对于老年组，病例数增加得非常显著，形成了一个傍晚高峰。青年至中年病例的SD百分比在夏季高于其他季节，这可能是夏季未出现显著昼夜变化的原因。
