Ares Manuel, Proudfoot Nick J
Department of Molecular Cell and Developmental Biology, University of California, Santa Cruz, Santa Cruz, CA 95064, USA.
Cell. 2005 Jan 28;120(2):163-6. doi: 10.1016/j.cell.2005.01.002.
The synthesis of mRNA by RNA polymerase II appears coupled to numerous RNA-processing events, based on physical or functional connections revealed by biochemical or genetic tests. New findings were presented at a recent meeting in Spain that begin to illuminate the mechanisms underlying the connections between mRNA processing and specific steps in transcription (initiation, elongation, and termination) as well as recombination.
基于生化或遗传学测试所揭示的物理或功能联系，RNA聚合酶II合成mRNA的过程似乎与众多RNA加工事件相关联。在西班牙最近召开的一次会议上展示了一些新发现，这些发现开始阐明mRNA加工与转录（起始、延伸和终止）以及重组的特定步骤之间联系的潜在机制。
