白细胞与基质相互作用在慢性炎症性关节疾病中的作用。
The role of leukocyte-stromal interactions in chronic inflammatory joint disease.
作者信息
Burman Angela, Haworth Oliver, Bradfield Paul, Parsonage Greg, Filer Andrew, Thomas Andrew M C, Amft Nicole, Salmon Mike, Buckley Christopher D
机构信息
Rheumatology Research Group, Institute for Biomedical Research, Division of Immunity and Infection, MRC Centre for Immune Regulation, University of Birmingham, Birmingham B15 2TT, UK.
出版信息
Joint Bone Spine. 2005 Jan;72(1):10-6. doi: 10.1016/j.jbspin.2004.03.009.
Abstract
Rheumatoid arthritis (RA) is a debilitating, chronic, persistent inflammatory disease that is characterised by painful and swollen joints. The aetiology of RA is unknown, however whereas past research has concentrated on the role of immune or inflammatory infiltrating cells in inflammation, it is becoming clear that stromal cells play a critical part in regulating the quality and duration of an inflammatory response. In this review we assess the role of fibroblasts within the inflamed synovium in modulating immune responses; in particular we examine the role of stromal cells in the switch from resolving to persistent inflammation as is found in the rheumatoid synovium.
摘要
类风湿性关节炎（RA）是一种使人衰弱的慢性持续性炎症性疾病，其特征为关节疼痛和肿胀。RA的病因尚不清楚，然而，尽管过去的研究集中在免疫或炎症浸润细胞在炎症中的作用，但越来越明显的是，基质细胞在调节炎症反应的质量和持续时间方面起着关键作用。在这篇综述中，我们评估了炎症滑膜中成纤维细胞在调节免疫反应中的作用；特别是我们研究了基质细胞在类风湿滑膜中从炎症消退到持续炎症转变过程中的作用。
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本文引用的文献
1
Regulation of the chemokine receptor CXCR4 by hypoxia.
J Exp Med. 2003 Nov 3;198(9):1391-402. doi: 10.1084/jem.20030267.
2
Global gene expression profiles in fibroblasts from synovial, skin and lymphoid tissue reveals distinct cytokine and chemokine expression patterns.
Thromb Haemost. 2003 Oct;90(4):688-97. doi: 10.1160/TH03-04-0208.
3
Cancer: cues for migration.
Nature. 2003 Sep 18;425(6955):247-8. doi: 10.1038/425247a.
4
Synoviocyte-mediated expansion of inflammatory T cells in rheumatoid synovitis is dependent on CD47-thrombospondin 1 interaction.
J Immunol. 2003 Aug 15;171(4):1732-40. doi: 10.4049/jimmunol.171.4.1732.
5
Selective imprinting of gut-homing T cells by Peyer's patch dendritic cells.
Nature. 2003 Jul 3;424(6944):88-93. doi: 10.1038/nature01726.
6
Synoviocyte-derived CXCL12 is displayed on endothelium and induces angiogenesis in rheumatoid arthritis.
J Immunol. 2003 Feb 15;170(4):2147-52. doi: 10.4049/jimmunol.170.4.2147.
7
IL-6: a regulator of the transition from neutrophil to monocyte recruitment during inflammation.
Trends Immunol. 2003 Jan;24(1):25-9. doi: 10.1016/s1471-4906(02)00013-3.
8
Isolation and characterization of bone marrow multipotential mesenchymal progenitor cells.
Arthritis Rheum. 2002 Dec;46(12):3349-60. doi: 10.1002/art.10696.
9
Endogenous lipid- and peptide-derived anti-inflammatory pathways generated with glucocorticoid and aspirin treatment activate the lipoxin A4 receptor.
Nat Med. 2002 Nov;8(11):1296-302. doi: 10.1038/nm786. Epub 2002 Oct 7.
10
Chemokines: agents for the immunotherapy of cancer?
Nat Rev Immunol. 2002 Mar;2(3):175-84. doi: 10.1038/nri748.
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