Adebamowo Clement A, Spiegelman Donna, Danby F William, Frazier A Lindsay, Willett Walter C, Holmes Michelle D
Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts 02115, USA.
J Am Acad Dermatol. 2005 Feb;52(2):207-14. doi: 10.1016/j.jaad.2004.08.007.
Previous studies suggest possible associations between Western diet and acne. We examined data from the Nurses Health Study II to retrospectively evaluate whether intakes of dairy foods during high school were associated with physician-diagnosed severe teenage acne.
We studied 47,355 women who completed questionnaires on high school diet in 1998 and physician-diagnosed severe teenage acne in 1989. We estimated the prevalence ratios and 95% confidence intervals of acne history across categories of intakes.
After accounting for age, age at menarche, body mass index, and energy intake, the multivariate prevalence ratio (95% confidence intervals; P value for test of trend) of acne, comparing extreme categories of intake, were: 1.22 (1.03, 1.44; .002) for total milk; 1.12 (1.00, 1.25; .56) for whole milk; 1.16 (1.01, 1.34; .25) for low-fat milk; and 1.44 (1.21, 1.72; .003) for skim milk. Instant breakfast drink, sherbet, cottage cheese, and cream cheese were also positively associated with acne.
We found a positive association with acne for intake of total milk and skim milk. We hypothesize that the association with milk may be because of the presence of hormones and bioactive molecules in milk.
先前的研究表明西方饮食与痤疮之间可能存在关联。我们分析了护士健康研究II的数据,以回顾性评估高中时期乳制品摄入量与医生诊断的重度青少年痤疮之间是否存在关联。
我们研究了47355名女性,她们在1998年完成了关于高中饮食的问卷调查,并在1989年接受了医生诊断的重度青少年痤疮检查。我们估计了不同摄入量类别中痤疮病史的患病率比值和95%置信区间。
在考虑年龄、初潮年龄、体重指数和能量摄入后,比较摄入量极端类别的痤疮多变量患病率比值(95%置信区间;趋势检验P值)分别为:全脂牛奶为1.22(1.03,1.44;.002);全脂牛奶为1.12(1.00,1.25;.56);低脂牛奶为1.16(1.01,1.34;.25);脱脂牛奶为1.44(1.21,1.72;.003)。即食早餐饮料、果汁牛奶冻、农家干酪和奶油芝士也与痤疮呈正相关。
我们发现全脂牛奶和脱脂牛奶的摄入量与痤疮呈正相关。我们推测与牛奶的关联可能是由于牛奶中存在激素和生物活性分子。