Ishioka Katsumi, Okumura Masahiro, Sagawa Mayumi, Nakadomo Fumio, Kimura Kazuhiro, Saito Masayuki
Laboratory of Biochemistry, Department of Biomedical Sciences, Graduate School of Veterinary Medicine, Hokkaido University, Sapporo 060-0818, Japan.
Vet Radiol Ultrasound. 2005 Jan-Feb;46(1):49-53. doi: 10.1111/j.1740-8261.2005.00009.x.
Obesity is the most common nutritional disorder in small animals. To establish a computed tomographic (CT) method for assessment of visceral and subcutaneous fat content in the dog, CT analysis was performed in normal and obese beagles. Fat area was measured by the level detection method at varied attenuation ranges and compared with body fat content estimated by the deuterium oxide dilution method. Fat area measured at L3 using the attenuation range of -135/-105 Hounsfield unit had the best correlation with body fat content (r = 0.98). Regional fat distribution was almost the same between normal and obese dogs, with more fat accumulation at L1-S1 than T10-T13. Moreover, visceral and subcutaneous fat area could be estimated separately. This CT method may contribute to both the clinical diagnosis and the study of canine obesity, especially for studies in the relationship between body fat distribution and obesity-associated diseases.
肥胖是小型动物中最常见的营养紊乱疾病。为建立一种用于评估犬内脏和皮下脂肪含量的计算机断层扫描(CT)方法,对正常和肥胖的比格犬进行了CT分析。通过在不同衰减范围内的水平检测方法测量脂肪面积,并与通过氧化氘稀释法估算的体脂含量进行比较。使用-135/-105亨氏单位的衰减范围在L3处测量的脂肪面积与体脂含量具有最佳相关性(r = 0.98)。正常犬和肥胖犬之间的区域脂肪分布几乎相同,L1-S1处的脂肪堆积比T10-T13处更多。此外,可以分别估算内脏和皮下脂肪面积。这种CT方法可能有助于犬肥胖的临床诊断和研究,特别是对于体脂分布与肥胖相关疾病之间关系的研究。